CEACAM5 Antikörper

Produktnummer ABIN111951

Produktdetails anti-CEACAM5 Antikörper

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: C19 is useful to detect CEA in malignant adenocarcinoma, notably in the gastro-intestinal tract. Clinical relevance is also found in breast-, lung-, prostatic-,ovarian- and other carcinomas of endodermal origin (stomach, liver, pancreas). Contrary to some other antibodies, C19 stains granulocytes in blood smears and tonsils, as well as epithelial cells.

Aufreinigung: Affinity chromatography.

Klon: C19

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Suitable for Immunohistochemistry on paraffin embedded sections (0.1 μg/mL, 1/4000). Microwave pretreatment forantigen retrieval is recommended. Suggested positive control: Human colon carcinoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Protokoll: Protocol with formalin-fixed, paraffin-embedded sections: The whole procedure is performed at room temperature

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 0.5 mL distilled water.

Konzentration: 0.4 mg/mL

Buffer: PBS, pH 7.2 with 10 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.01 % thimerosal as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu CEACAM5

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Andere Bezeichnung: CD66e / CEACAM5 (CEACAM5 Produkte)

Synonyme: CD66e antikoerper, CEA antikoerper, CEACAM5 antikoerper, CEACAM antikoerper, 1600029H12Rik antikoerper, Psg30 antikoerper, carcinoembryonic antigen related cell adhesion molecule 5 antikoerper, carcinoembryonic antigen antikoerper, carcinoembryonic antigen-related cell adhesion molecule 5 antikoerper, carcinoembryonic antigen-related cell adhesion molecule 8 antikoerper, carcinoembryonic antigen gene family antikoerper, CEACAM5 antikoerper, Ceacam5 antikoerper, LOC100409241 antikoerper, Cea antikoerper

Hintergrund: CEA is a glycoprotein of 180 kDa m.w. It is a normal constituent of the glycocalix of embryonic endodermal epithelium and is produced mainly in the mucosa of the normal colon.Synonyms: CEA, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, Meconium antigen 100

Gen-ID: 1048

NCBI Accession: NP_004354

UniProt: P06731