Substance P Antikörper
| Antigen |
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| Synonyme |
NK2, NPK, NKNA, TAC2, Hs.2563, SP, NK1, NK-1, Nkna, PPT-A, MGC151458, 4930528L02Rik |
| Klonalität |
Monoklonal (SMPS59-1) |
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Wirt
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Reaktivität
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Human (39), Ratte (Rattus) (27), Maus (22), Meerschweinchen (17), Rind (Kuh) (16), Kaninchen (16), Pferd (15), Schaf (15), Säugetiere (2), Huhn (1), Fisch (1), Affe (1), Schwein (1)
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Applikation
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 Alternativen Enzyme Immunoassay (EIA), Immunfluoreszenz (IF)
Immunfluoreszenz (IF) (30), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (21), Durchflusszytometrie (FACS) (19), Immunhistochemie (Paraffinschnitte) (IHC (p)) (17), ELISA (8), Immunhistochemie (IHC) (7), Western Blot (WB) (4), Enzyme Immunoassay (EIA) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunpräzipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Radioimmunoassay (RIA) (1)
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| Produktnummer |
ABIN111462 |
| Menge |
0.1 mg (1.0 mg/ml (prior to lyophilization)) |
| Preis |
500,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: Substance-P
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Gen-ID
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6863
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Swiss-Prot
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P20366
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Immunogen
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Synthetic human Substance P peptide. AA Sequence: R-P-R-P-Q-Q-F-F-G-L-M
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Isotyp
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IgG1 (Passende Sekundärantikörper)
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Klon
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SMPS59-1
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Beschreibung
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Substance P (SP) is currently thought to be one of the most important neurotransmittersand neurotransmitters in the brain. It is an undecapeptide belonging to the tachykininfamily, which consists of excitatory neuropeptides synthesised in neuronal and glial cellsof the human central and peripheral nervous system. Substance P, Neurokinin A,Neuropeptide K, and Neuropeptide gamma are all generated by post-translation cleavageof the precursor Protachykinin-1. Substance P forms the major endogenous ligand forNeurokinin 1 Receptor. The pharmacology of Substance P has been associated with anumber of neurological and psychiatric disorders, namely nociception, migraine, asthma,nausea, inflammatory bowel syndrome, urinary incontinence, anxiety and depression. Ithas also been linked to obesity.
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Spezifität
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Reacts specifically with human substance P. No cross reactivity against Neurokinin A, Neurokinin B or Kassinin.
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Applikationshinweise
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Suitable for use in ELISA (1: 10,000) and Immunostaining (1: 1,000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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1.0 mg/ml (prior to lyophilization)
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Buffer
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0.1 M Glycine PBS, pH 7.4 without preservatives.Reconstitution: Reconstitute in 10 µl double distilled water.
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Lagerung
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Store lyophilized (preferably in a desiccator) at 2-8°C and reconstituted (in aliquots) at-20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Forschungsgebiet
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Neurologie, Zell-/Gewebemarker
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Substance P", Typ "Antikörper" finden
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Wirte
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Kaninchen (37), Maus (8), Meerschweinchen (4), Ratte (3)
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Reaktivitäten
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Human (39), Ratte (Rattus) (27), Maus (22), Meerschweinchen (17), Rind (Kuh) (16), Kaninchen (16), Pferd (15), Schaf (15), Säugetiere (2), Huhn (1), Fisch (1), Affe (1), Schwein (1)
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Applikationen
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Immunfluoreszenz (IF) (30), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (21), Durchflusszytometrie (FACS) (19), Immunhistochemie (Paraffinschnitte) (IHC (p)) (17), ELISA (8), Immunhistochemie (IHC) (7), Western Blot (WB) (4), Enzyme Immunoassay (EIA) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunpräzipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Radioimmunoassay (RIA) (1)
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Konjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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AA 4-11 (2)
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