Blood Group Antikörper

Antigen: Blood Group

Klonalität: Monoklonal (HEB-29)

Wirt: Maus

Reaktivität: Human

Applikation: Aggregation (AGG), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN111336

Produktbeschreibung

Produktmerkmale: Synonyms: Blood Group B Antigen

Immunogen: Mixture of erythrocytes of group B and glycoprotein fraction isolated from saliva ofsecretors with blood group B.

Format: Supernatant

Isotyp: IgM  (Passende Sekundärantikörper)

Klon: HEB-29

Beschreibung: Blood group antigens are generally defined as molecules formed by sequential addition ofsaccharides to the carbohydrate side chains of lipids and proteins detected onerythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergomodulation during malignant cellular transformation. Blood group related antigensrepresent a group of carbohydrate determinants carried on both glycolipids andglycoproteins. They are usually mucin type, and are detected on erythrocytes, certainepithelial cells, and in secretions of certain individuals. Sixteen genetically andbiosynthetically distinct but inter related specificities belong to this group of antigens,including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Spezifität: The antibody reacts with Human Blood Group B. The specifity of the antibody was confirmed by comparison of specifity and reactivity tostandard reagent using > 5. 000 samples of blood. Species: Human. Others not tested.

Anwendungen

Applikationshinweise: Agglutination. Immunohistochemistry on Paraffin Sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Lagerung: Store the antibody at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Vanak, Drimalova, Smyslova et al.: "Detection of blood group A antigen expression in human colon cancer using monoclonal antibodies with different specificities." in: Neoplasma, Vol. 36, Issue 4, pp. 479-88, 1989 (PubMed).