Blood Group A1B Antigen Antikörper

Antigen: Blood Group A1B Antigen

Klonalität: Monoklonal (HE-24)

Wirt: Maus

Reaktivität: Human

Applikation: Aggregation (AGG)

Produktnummer: ABIN111319

Produktbeschreibung

Immunogen: Glycoprotein fraction isolated from saliva of secretors with blood group A

Format: Supernatant

Isotyp: IgM

Klon: HE-24

Spezifität: This antibody recognizes a determinant topographically related to terminalN-acetyl-D-galactosamine in blood group A specific trisacharride. Haemagglutinationactivity is inhibited by D-GalNac. The A antigen is widely distributed in the erythrocytescells and tissues and body fluids of A positive individuals. The reactive group GalNAca1-Ser(or Thr) is exposed in sialoglycoproteins of individuals with Tn syndrome irrespective oftheir A antigen status. The antibody HE-24 distinguishes blood group A1B from A2B. Thespecifity of the antibody was verified on > 1000 samples of blood. Species: Human. Others not tested.

Anwendungen

Applikationshinweise: Agglutination. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Lagerung: Store the antibody at 2 - 8 °C. Do not freeze. Shelf life: one year from despatch.

Forschungsgebiet: Zell-/Gewebemarker, Blutgruppen-Antigene

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Vanak, Drimalova, Smyslova et al.: "Detection of blood group A antigen expression in human colon cancer using monoclonal antibodies with different specificities." in: Neoplasma, Vol. 36, Issue 4, pp. 479-88, 1989 (PubMed).