TFPI2 Antikörper (Middle Region)

Produktnummer ABIN1109225

Produktdetails anti-TFPI2 Antikörper

Target: TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFPI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects TFPI2 (Middle). No cross reactivity with other proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the Middle region of human TFPI2 .Remarks: Sequence is identical to the related rat and mouse sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu TFPI2

Target: TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))

Andere Bezeichnung: TFPI2 (TFPI2 Produkte)

Synonyme: MGC68843 antikoerper, TFPI2 antikoerper, MGC108301 antikoerper, si:ch211-262k23.2 antikoerper, tfpi2 antikoerper, PP5 antikoerper, REF1 antikoerper, TFPI-2 antikoerper, AV000670 antikoerper, PP5/TFPI-2 antikoerper, tissue factor pathway inhibitor 2 L homeolog antikoerper, tissue factor pathway inhibitor 2 antikoerper, tfpi2.L antikoerper, TFPI2 antikoerper, tfpi2 antikoerper, Tfpi2 antikoerper

Hintergrund: Tissue factor pathway inhibitor 2, also known as TFPI2, is a human gene which is located at 7q22. It is an important regulator of the extrinsic pathway of blood coagulation through its ability to inhibit factor Xa and factor VIIa-tissue factor activity. After a 22-residue signal peptide, the mature TFPI2 protein contains 213 amino acids with 18 cysteines and 2 canonical N-linked glycosylation sites. The purified recombinant TFPI2 strongly inhibited the amidolytic activities of trypsin and the factor VIIa-tissue factor complex. The latter inhibition was markedly enhanced in the presence of heparin. Mouse TFPI2 mRNA is highly expressed in developing mouse placenta, as in human. And there are also high transcript levels in adult mouse liver and kidney.Synonyms: PP5, Placental protein 5, TFPI-2, Tissue factor pathway inhibitor 2

Gen-ID: 7980

NCBI Accession: NP_006519

UniProt: P48307