SYT1 Antikörper

Produktnummer ABIN1109184

Produktdetails anti-SYT1 Antikörper

Target: SYT1 (Synaptotagmin I (SYT1))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SYT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Spezifität: This antibody reacts with Synaptotagmin 1 and 2 (58 kDa/60 kDa) on Western blotting. Synaptotagmin 1 has a predicted molecular weight of 47 kDa but it migrates at ~65 kDa. It is reported that this clone (1D12) recognizes rat synaptotagmin residues (99-104 aa) in the reference number 17).

Kreuzreaktivität (Details): Species reactivity (tested):Rat

Aufreinigung: Protein A agarose

Immunogen: Chicken brain synaptic membrane

Klon: 1D12

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2, without preservatives

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store (in aliquots) at -20 °C.

Details zu SYT1

Target: SYT1 (Synaptotagmin I (SYT1))

Andere Bezeichnung: Synaptotagmin-1 (SYT1 Produkte)

Synonyme: P65 antikoerper, SVP65 antikoerper, SYT antikoerper, CG3139 antikoerper, D. Syt I antikoerper, DSYT antikoerper, DSYT2 antikoerper, DSypt antikoerper, DSyt antikoerper, Dmel\\CG3139 antikoerper, Droso1 antikoerper, Dsyt2 antikoerper, SYT I antikoerper, SYT1 antikoerper, Syt antikoerper, Syt 1 antikoerper, Syt I antikoerper, Syt-1 antikoerper, SytI antikoerper, dSYT antikoerper, dsyt1 antikoerper, dsytI antikoerper, l(2)23AB1 antikoerper, l(2)23Ba antikoerper, l(2)k05909 antikoerper, syt antikoerper, syt 1 antikoerper, syt I antikoerper, syt-1 antikoerper, syt1 antikoerper, sytI antikoerper, AW124717 antikoerper, G630098F17Rik antikoerper, Syti antikoerper, GB20036 antikoerper, DKFZP459P193 antikoerper, svp65 antikoerper, p65 antikoerper, wu:fj41c01 antikoerper, wu:fk56d05 antikoerper, zgc:92899 antikoerper, synaptotagmin 1 antikoerper, Synaptotagmin 1 antikoerper, synaptotagmin I antikoerper, synaptotagmin-1 antikoerper, synaptotagmin, p65 antikoerper, synaptotagmin Ia antikoerper, synaptotagmin 1 L homeolog antikoerper, SYT1 antikoerper, Syt1 antikoerper, Tsp_06980 antikoerper, Tsp_08220 antikoerper, syt1 antikoerper, LOC100533340 antikoerper, syt1a antikoerper, syt1.L antikoerper

Hintergrund: Synaptotagmins are a family of at least 15 Ca2+-binding, membrane-trafficking proteins that act as calcium sensors regulating neurotransmitter release. Synaptotagamins are expressed in both vesicular and plasma membranes where they are involved in lipid rearrangements required during synaptic vesicle fusion. Synaptotagmins also interact with calcium channels, sodium channels, b-SNAP, neurexins, and other neural proteins in the absence of Ca2+, suggesting a role in presynaptic functions. Synaptotagmins exhibit differential expression, with synaptotagmins 1-5 expressed primarily in neural and endocrine tissues. Northern blots in murine brain tissue suggest synaptotagmin 1 is primarily expressed in rostral brain regions but has low expression in regions related to motor functions.Synonyms: SVP65, SYT, SYT2, Synaptotagmin I, Synaptotagmin II, Synaptotagmin1, Synaptotagmin2, Synonyms: SYT1, SytI, SytII, p65

Gen-ID: 6857

NCBI Accession: NP_001129277

UniProt: P21579

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport