Surfactant Protein C Antikörper (N-Term)

Produktnummer ABIN1108993

Produktdetails anti-Surfactant Protein C Antikörper

Target: Surfactant Protein C (SFTPC)

Bindungsspezifität: AA 1-33, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Surfactant Protein C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody detects pro-SP-C (AA 1-33).

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Purified

Immunogen: Recombinant human pro-SP-C (AA 1-33), GST fusion

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu Surfactant Protein C

Target: Surfactant Protein C (SFTPC)

Andere Bezeichnung: SFTPC (SFTPC Produkte)

Synonyme: SFTPC antikoerper, SPC antikoerper, SP-C antikoerper, psp-c antikoerper, sftp2 antikoerper, xSP-C antikoerper, Bricd6 antikoerper, SP5 antikoerper, Sftp-2 antikoerper, Sftp2 antikoerper, pro-SpC antikoerper, BRICD6 antikoerper, PSP-C antikoerper, SFTP2 antikoerper, SMDP2 antikoerper, surfactant protein C antikoerper, surfactant, pulmonary-associated protein C S homeolog antikoerper, surfactant, pulmonary-associated protein C antikoerper, surfactant associated protein C antikoerper, SFTPC antikoerper, sftpc.S antikoerper, sftpc antikoerper, Sftpc antikoerper

Hintergrund: There are four surfactant-specific proteins, designated surfactant protein A (SP-A), SP-B, SP-C and SP-D respectively. SP-A and SP-D are hydrophilic surfactant proteins and are members of the collectin family. SP-B and SP-C are hydrophobic surfactant proteins and may be the most appropriate indicators for the evolutionary origin of surfactant. SP-C is a 34-35 amino acid peptide, of 4 kD that is proteolytically processed from a 21 kD precursor protein. SP-C is initiated early in the embryogenic period of lung formation, where SP-C transcripts are detected uniformly in epithelial cells lining the primitive airways. During lung development SP-C expression is decreased in cells of the proximal conducting portion of the lung. Ultimately SP-C is expressed selectively in type II epithelial cells in the alveolus of the lung. SP-C is secreted into the airspace where it enhances the spreading and stability of surfactant phospholipids in the alveolus. SP-C plays an important role in the spreading and stabilization of phospholipid films in the alveolus. SP-C is essential for air-breathing in mammals and is therefore largely conserved. Deficiency of SP-C and other surfactant components is associated with respiratory distress syndrome (RDS) in premature infants and adults with respiratory distress syndrome (ARDS).Synonyms: Pulmonary surfactant-associated protein C, Pulmonary surfactant-associated proteolipid SPL(Val), SFTP2, SP-C, SP5, Surfactant protein C

Gen-ID: 6440

NCBI Accession: NP_001165828

UniProt: P11686