S100A8 Antikörper
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- Target Alle S100A8 Antikörper anzeigen
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser S100A8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes an epitope on the S100A8 (MRP-8) protein.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Protein G
- Klon
- 7C12-4
- Isotyp
- IgM
- Top Product
- Discover our top product S100A8 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/mL
- Buffer
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C.
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- Target
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
- Andere Bezeichnung
- S100A8 / Calgranulin-A / MRP8 (S100A8 Produkte)
- Synonyme
- 60B8AG antikoerper, CAGA antikoerper, CFAG antikoerper, CGLA antikoerper, CP-10 antikoerper, L1Ag antikoerper, MA387 antikoerper, MIF antikoerper, MRP8 antikoerper, NIF antikoerper, P8 antikoerper, Mrp8 antikoerper, S100A8 antikoerper, 60B8Ag antikoerper, AI323541 antikoerper, B8Ag antikoerper, CFAg antikoerper, Caga antikoerper, p8 antikoerper, MRP-8 antikoerper, S100 calcium binding protein A8 antikoerper, S100 calcium binding protein A8 (calgranulin A) antikoerper, S100A8 antikoerper, S100a8 antikoerper
- Hintergrund
- The calcium-binding, migration inhibitory factor-related proteins, MRP-8 (S100A8) and MRP-14 (S100A9) belong to the S100 protein family. The expression of these proteins is largely confined to the cytosol of neutrophils and monocytes. The complex formation of these proteins is a calcium-dependent process. The S100A8/A9 heterocomplex, also called MRP-8/MRP-14 complex or calprotectin, comprises 60 % of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils. In inflammatory conditions small venueles stain with both anti-S100A8 and S100A9. The staining of the two subunits is always coincident. The S100A8/A9 complex has antibacterial, antifungal and immunomodulating and antiproliferative effects. Besides this it is a potent chemotactic factor for neutrophils.Synonyms: CAGA, CFAG, Calprotectin L1L subunit, Cystic fibrosis antigen, Leukocyte L1 complex light chain, MRP-8, Migration inhibitory factor-related protein 8, S100 calcium-binding protein A8, S100-A8, Urinary stone protein band A
- Gen-ID
- 6279
- NCBI Accession
- NP_002955
- UniProt
- P05109
- Pathways
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteine
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