PADI2 Antikörper (C-Term)

Produktnummer ABIN1108563

Produktdetails anti-PADI2 Antikörper

Target: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PADI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Spezifität: Reacts with 76 kDa PAD2 protein. No cross reaction with the other isoforms.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse and Rat.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide derived from C-terminal domain of the Human PAD-2 protein.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in distilled water.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PADI2

Target: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Andere Bezeichnung: PADI2 (PADI2 Produkte)

Synonyme: PADI2 antikoerper, PAD-H19 antikoerper, PAD2 antikoerper, PDI2 antikoerper, Pdi antikoerper, Pdi2 antikoerper, mKIAA0994 antikoerper, peptidyl arginine deiminase 2 antikoerper, peptidyl arginine deiminase, type II antikoerper, protein-arginine deiminase type-2 antikoerper, peptidyl arginine deiminase, type II S homeolog antikoerper, PADI2 antikoerper, padi2 antikoerper, LOC100357368 antikoerper, padi2.S antikoerper, Padi2 antikoerper

Hintergrund: PADI2 / PAD2 is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. Each family member has a distinct substrate specificity and tissue expression pattern. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative disorders, including Alzheimers disease and multiple sclerosis, and it has also been implicated in the pathogenesis of glaucoma.Synonyms: KIAA0994, PAD-H19, PDI2, Peptidylarginine deiminase II, Protein-arginine deiminase type II, Protein-arginine deiminase type-2

Gen-ID: 11240

NCBI Accession: NP_031391