Occludin Antikörper (OCLN) (AA 358-504)

Details for Product anti-OCLN Antibody No. ABIN1108503, Anbieter: Anmelden zum Anzeigen
Antigen
  • tpmt
  • OCLN
  • BLCPMG
  • AI503564
  • Ocl
  • ocln
  • oclnb
  • wu:fd23h10
  • wu:fi13c01
  • zgc:113992
  • zgc:56359
  • occludin
  • occludin a
  • OCLN
  • ocln
  • Ocln
  • ocln-b
  • oclna
Epitop
AA 358-504
34
15
13
7
7
6
5
5
4
4
3
3
2
1
1
1
Reaktivität
Hund, Human, Maus, Ratte (Rattus)
115
56
50
17
16
4
4
4
3
2
2
2
Wirt
Meerschweinchen
87
33
2
Klonalität
Polyklonal
Konjugat
Dieser Occludin Antikörper ist unkonjugiert
6
6
5
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
104
55
28
25
25
13
10
7
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Recombinant Human Occludin (aa 358-504)
Isotyp Ig
Spezifität The polyclonal antibody reacts with Occludin.
Kreuzreaktivität (Details) Species reactivity (tested):Human, Mouse, Rat, Canine.
Reinigung Protein A Chromatography
Andere Bezeichnung Occludin (OCLN Antibody Abstract)
Hintergrund Occludin is an integral membrane protein specifically associated with tight junctions. These specialized regions of the plasma membrane prevent the diffusion of dissolved molecules between adjacent epithelial cells, seal off body cavities such as intestine or stomach lumen and prevent the diffusion of membrane proteins and glycolipids between the apical and basolateral regions of the plasma membrane. Occludin is localized at tight junctions of both epithelial and endothelial cells and is highly expressed in kidney and has not been detected in testis. On the cytoplasmic surface of occludin, a domain within the C-terminal 150 residues has been shown to bind directly to the well-characterized tight junction protein zona occludens 1 (ZO-1).Synonyms: OCLN
Gen-ID 100506658
NCBI Accession NP_001192183
UniProt Q16625
Pathways Cell-Cell Junction Organization, Hepatitis C
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 0.1 mg/mL
Buffer PBS, 0.02 % Sodium Azide, 0.1 % BSA
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store undiluted at 2-8 °C.
Allgemeine Veröffentlichungen Van Itallie, Anderson: "Occludin confers adhesiveness when expressed in fibroblasts." in: Journal of cell science, Vol. 110 ( Pt 9), pp. 1113-21, 1997 (PubMed).

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