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Endothelin 1 Antikörper (C-Term)

EDN1 Reaktivität: Human RIA, IHC (fro) Wirt: Ratte Monoclonal 3G10 unconjugated
Produktnummer ABIN110809
  • Target Alle Endothelin 1 (EDN1) Antikörper anzeigen
    Endothelin 1 (EDN1)
    Bindungsspezifität
    • 20
    • 16
    • 15
    • 13
    • 11
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 121
    • 44
    • 31
    • 22
    • 4
    • 3
    • 1
    • 1
    Human
    Wirt
    • 113
    • 33
    • 1
    Ratte
    Klonalität
    • 115
    • 32
    Monoklonal
    Konjugat
    • 61
    • 23
    • 17
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Endothelin 1 Antikörper ist unkonjugiert
    Applikation
    • 112
    • 64
    • 48
    • 33
    • 26
    • 22
    • 13
    • 13
    • 12
    • 11
    • 11
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    Radioimmunoassay (RIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Sequenz
    C-H-L-D-I-I-W
    Spezifität
    Reacts with the C-terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin.
    Aufreinigung
    Protein G affinity chromatography
    Immunogen
    Synthetic human endothelin-C terminal fragment, conjugated to BSA
    Klon
    3G10
    Isotyp
    IgG2b
    Top Product
    Discover our top product EDN1 Primärantikörper
  • Applikationshinweise
    RIA / IRMA. Immunohistochemistry on frozen sections: Frozen sections processed with dry acetone are recommended. Paraformaldehyde is notrecommended as it destroys the epitope.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS, containing 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Endothelin 1 (EDN1)
    Andere Bezeichnung
    Endothelin-1 (EDN1 Produkte)
    Synonyme
    et1 antikoerper, et-1 antikoerper, Edn1 antikoerper, EDN antikoerper, ET-1 antikoerper, ET1 antikoerper, PPET1 antikoerper, HDLCQ7 antikoerper, preproET antikoerper, Et1 antikoerper, fb14d01 antikoerper, wu:fb14d01 antikoerper, PPET-1 antikoerper, EDN1 antikoerper, edn1 antikoerper, edn1-a antikoerper, edn1-b antikoerper, endothelin 1 antikoerper, endothelin 1 S homeolog antikoerper, endothelin 1 L homeolog antikoerper, edn1 antikoerper, EDN1 antikoerper, Edn1 antikoerper, edn1.S antikoerper, edn1.L antikoerper
    Hintergrund
    Endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.Synonyms: Big endothelin-1, EDN1, EDN2, ET-2, ET-3, Endothelin-2, Endothelin1, PPET1, PPET2, PPET3, Preproendothelin-1, Preproendothelin-2, Preproendothelin-3
    Gen-ID
    1906
    NCBI Accession
    NP_001946
    UniProt
    P05305
    Pathways
    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
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