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IL27 Antikörper

IL27 Reaktivität: Human FACS Wirt: Maus Monoclonal B-G49 unconjugated
Produktnummer ABIN1107834
  • Target Alle IL27 Antikörper anzeigen
    IL27 (Interleukin-27 Subunit alpha (IL27))
    Reaktivität
    • 16
    • 14
    • 10
    Human
    Wirt
    • 16
    • 3
    Maus
    Klonalität
    • 16
    • 3
    Monoklonal
    Konjugat
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL27 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Flow Cytometry (FACS)
    Spezifität
    Recognizes both natural and recombinant Human IL-27
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Ion Exchange Chromatography.
    Sterilität
    0.22 μm filtered
    Immunogen
    Recombinant Human IL-27.
    Klon
    B-G49
    Isotyp
    IgG2a
    Top Product
    Discover our top product IL27 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    IL27 (Interleukin-27 Subunit alpha (IL27))
    Andere Bezeichnung
    Interleukin-27 / IL27A (IL27 Produkte)
    Synonyme
    IL-27 antikoerper, IL-27A antikoerper, IL27A antikoerper, IL27p28 antikoerper, IL30 antikoerper, p28 antikoerper, EUROIMAGE1875335 antikoerper, IL25 antikoerper, IL27 antikoerper, IL27w antikoerper, R33729_1 antikoerper, SF20 antikoerper, IL-27p28 antikoerper, Il30 antikoerper, interleukin 27 antikoerper, myeloid derived growth factor antikoerper, IL27 antikoerper, MYDGF antikoerper, Il27 antikoerper
    Hintergrund
    Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28
    Gen-ID
    246778
    NCBI Accession
    NP_663634
    UniProt
    Q8NEV9
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