SEMA7A Antikörper

Produktnummer ABIN110773

Produktdetails anti-SEMA7A Antikörper

Target: SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SEMA7A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)

Spezifität: The antibody reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored glycoprotein expressed on various cell types including erythrocytes, lymphoblasts, at low levels it is present on circulating lymphocytes.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Ion exchange chromatography

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: HPB-ALL human T cell line

Klon: MEM-150

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. Immunoprecipitation. Western Blotting under non reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. Dilute only prior to immediate use

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SEMA7A

Target: SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))

Andere Bezeichnung: CD108 / SEMA7A (SEMA7A Produkte)

Synonyme: 2900057C09Rik antikoerper, CDw108 antikoerper, H-Sema-L antikoerper, M-Sema-L antikoerper, Semal antikoerper, CD108 antikoerper, H-SEMA-K1 antikoerper, JMH antikoerper, SEMAK1 antikoerper, SEMAL antikoerper, sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A antikoerper, semaphorin 7A (John Milton Hagen blood group) antikoerper, Sema7a antikoerper, SEMA7A antikoerper

Hintergrund: CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors plexin C1 and b1 integrins.Synonyms: JMH blood group antigen, John-Milton-Hargen human blood group Ag, SEMAL, Semaphorin-7A, Semaphorin-K1, Semaphorin-L

Gen-ID: 8482

NCBI Accession: NP_001139501

UniProt: O75326

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size