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IFNA1 Antikörper

IFNA1 Reaktivität: Maus FACS, Func, EIA Wirt: Ratte Monoclonal F18 unconjugated
Produktnummer ABIN1107635
  • Target Alle IFNA1 Antikörper anzeigen
    IFNA1 (Interferon, alpha 1 (IFNA1))
    Reaktivität
    • 70
    • 13
    • 3
    • 2
    • 2
    • 1
    Maus
    Wirt
    • 51
    • 22
    • 3
    Ratte
    Klonalität
    • 53
    • 23
    Monoklonal
    Konjugat
    • 37
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IFNA1 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 31
    • 14
    • 14
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognises most isoforms of natural and recombinant alpha Interferon. It does not cross-react with Murine beta or gamma Interferon, nor with Human alpha Interferon. The antibody exhibits neutralizing activity of approximately 6.25 x 10e4 neutralizing units/mg.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Mouse.
    Aufreinigung
    Protein G
    Klon
    F18
    Isotyp
    IgG1
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    PBS, 0.1 % BSA
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
    Haltbarkeit
    6 months
  • Target
    IFNA1 (Interferon, alpha 1 (IFNA1))
    Andere Bezeichnung
    IFNA1 / Interferon-alpha 1 (IFNA1 Produkte)
    Synonyme
    IFL antikoerper, IFN antikoerper, IFN-ALPHA antikoerper, IFN-alphaD antikoerper, IFNA13 antikoerper, IFNA@ antikoerper, Ifa1 antikoerper, IFN-ALPHA-1 antikoerper, IFN1@ antikoerper, IFNA1 antikoerper, IFN-alpha antikoerper, IFN-gamma antikoerper, IFNA antikoerper, IFNA2 antikoerper, IFNA6 antikoerper, IFN-alpha1 antikoerper, interferon alpha 13 antikoerper, interferon alpha 1 antikoerper, interferon, alpha 1 antikoerper, interferon, alpha 13 antikoerper, interferon antikoerper, interferon-alpha 1 antikoerper, interferon, alpha, leukocyte antikoerper, interferon-alpha-14 antikoerper, IFNA13 antikoerper, IFNA1 antikoerper, Ifna1 antikoerper, ifna1 antikoerper, IFNA3 antikoerper, IFN-ALPHA-14 antikoerper
    Hintergrund
    The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. Interferon alpha is produced primarily by plasmacytoid dendritic cells and is a potent component of the anti viral innate immune response, it modulates adaptive immunity. The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.Synonyms: IFN-alpha 1, IFNA13, Interferon alpha-D, LeIF D
    Gen-ID
    15962
    NCBI Accession
    NP_034632
    UniProt
    P01572
    Pathways
    JAK-STAT Signalweg, Hepatitis C
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