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Desmoglein 3 Antikörper

DSG3 Reaktivität: Human WB, IF, IP, IHC (p), IHC (fro) Wirt: Maus Monoclonal 5G11 unconjugated
Produktnummer ABIN1106983
  • Target Alle Desmoglein 3 (DSG3) Antikörper anzeigen
    Desmoglein 3 (DSG3)
    Reaktivität
    • 66
    • 21
    • 16
    Human
    Wirt
    • 60
    • 26
    Maus
    Klonalität
    • 60
    • 26
    Monoklonal
    Konjugat
    • 35
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Desmoglein 3 Antikörper ist unkonjugiert
    Applikation
    • 63
    • 35
    • 19
    • 18
    • 16
    • 13
    • 13
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    The monoclonal antibody 5G11 reacts with the 140 kDa desmoglein 3 protein. Furthermore it is not cross reactive with desmoglein 1 or desmoglein 2.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Protein G
    Klon
    5G11
    Isotyp
    IgG1
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Desmoglein 3 (DSG3)
    Andere Bezeichnung
    Desmoglein-3 (DSG3 Produkte)
    Synonyme
    DSG3 antikoerper, CDHF6 antikoerper, PVA antikoerper, bal antikoerper, balding antikoerper, desmoglein 3 antikoerper, DSG3 antikoerper, Dsg3 antikoerper
    Hintergrund
    Desmoglein 3 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 3 is synthesized in both the basal and the lower suprabasal compartments.Synonyms: 130 kDa pemphigus vulgaris antigen, CDHF6, Cadherin family member 6, DSG3, PVA
    Gen-ID
    1830
    NCBI Accession
    NP_001935
    UniProt
    P32926
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