Cyclin D2 Antikörper
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- Target Alle Cyclin D2 (CCND2) Antikörper anzeigen
- Cyclin D2 (CCND2)
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Reaktivität
- Human, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Cyclin D2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Spezifität
- This antibody reacts to Cyclin D2.
- Aufreinigung
- Affinity chromatography
- Immunogen
- Recombinant human cyclin D2 protein
- Klon
- CY-D2
- Isotyp
- IgG2a
- Top Product
- Discover our top product CCND2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Restore with 1.2 % sodium acetate or neutral PBS
- Konzentration
- 0,1 mg/mL
- Buffer
- 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Cyclin D2 (CCND2)
- Andere Bezeichnung
- Cyclin D2 (CCND2 Produkte)
- Synonyme
- si:ch211-240j22.2 antikoerper, ccnd2 antikoerper, CCND2 antikoerper, kiak0002 antikoerper, zgc:162280 antikoerper, LOC100224096 antikoerper, KIAK0002 antikoerper, BF642806 antikoerper, C86853 antikoerper, Vin-1 antikoerper, Vin1 antikoerper, cD2 antikoerper, 2600016F06Rik antikoerper, AI256817 antikoerper, cyclin D2, b antikoerper, cyclin D2 S homeolog antikoerper, cyclin D2 antikoerper, G1/S-specific cyclin-D2 antikoerper, cyclin D2, a antikoerper, cyclin D2 L homeolog antikoerper, ccnd2b antikoerper, ccnd2.S antikoerper, CCND2 antikoerper, ccnd2 antikoerper, ccnd2a antikoerper, Ccnd2 antikoerper, ccnd2.L antikoerper
- Hintergrund
- Cyclin D2, also known as CCND2, is a human gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin D1, Cyclin D2 and Cyclin D3 are the members of the cyclin family. Cyclin D2 mapped to 12p131, since the CCND1 gene is on 11q13, this may be another bit of evidence of the homology of chromosomes 11 and 12. Choi D et al proved the expression of pseudogene cyclin D2 mRNA in the human ovary increases with age, which may be a novel marker for decreased ovarian function associated with the aging process.2 And knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Inaba et al. (1992) used murine cDNA clones for 3 cyclin D genes that are normally expressed during the G1 phase of the cell cycle to clone the cognate human genes. D-type cyclins (cyclins D1, D2, and D3) are regarded as essential links between cell environment and the core cell cycle machinery. Cyclin D2(CCND2) gene ia assigned to 12p13.Synonyms: CCND2, Cyclin-D2
- Gen-ID
- 894
- NCBI Accession
- NP_001750
- UniProt
- P30279
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
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