CD40 Antikörper (CD40 Molecule, TNF Receptor Superfamily Member 5) (PE)

Details for Product anti-CD40 Antibody No. ABIN1106360, Anbieter: Anmelden zum Anzeigen
Antigen
  • AI326936
  • Bp50
  • GP39
  • HIGM1
  • IGM
  • IMD3
  • T-BAM
  • TRAP
  • Tnfrsf5
  • p50
  • CDW40
  • TNFRSF5
  • TNFSF5
  • 2310042E05Rik
  • C130077D06Rik
  • C87049
  • DCTN-50
  • GMP23-48K
  • RBP50
  • CD40 antigen
  • CD40 molecule, TNF receptor superfamily member 5
  • dynactin 2
  • LOC100349106
  • Cd40
  • CD40
  • Dctn2
Reaktivität
Human
658
331
69
20
14
10
10
6
4
3
2
2
1
1
1
1
Wirt
Maus
514
231
171
23
6
4
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser CD40 Antikörper ist konjugiert mit PE
87
85
50
27
25
24
20
18
14
13
12
10
10
10
9
9
9
9
9
9
9
8
7
6
6
5
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS)
608
247
207
157
112
103
103
65
47
36
19
18
15
13
10
8
6
6
3
3
3
3
2
2
1
1
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Raji cell line
Klon B-B20
Isotyp IgG1
Spezifität This antibody recognises the Bp50 antigen, a 48 kDa protein.
Reinigung Ion exchange chromatography
Andere Bezeichnung CD40 (CD40 Antibody Abstract)
Hintergrund Synonyms: B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5
Gen-ID 958
NCBI Accession NP_001241
UniProt P25942
Forschungsgebiet Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis, Inflammation, Cancer
Pathways NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Rekonstitution Restore with 1.0 mL deionised water.
Buffer Phosphate-buffered saline containing 1 % BSA as stabilizer and 0.09 % sodium azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung DO NOT FREEZE!
Lagerung 4 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C.
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) antibody (PE) (ABIN1106360) anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) antibody (PE)
Allgemeine Veröffentlichungen Iwamoto, Iwai, Tsujiyama, Kurahashi, Takeshita, Naoe, Masunaga, Ogawa, Oguchi, Miyazaki: "TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 3, pp. 1449-57, 2007 (PubMed).

Iwamoto, Ishida, Takahashi, Takeda, Miyazaki: "Lipopolysaccharide stimulation converts vigorously washed dendritic cells (DCs) to nonexhausted DCs expressing CD70 and evoking long-lasting type 1 T cell responses." in: Journal of leukocyte biology, Vol. 78, Issue 2, pp. 383-92, 2005 (PubMed).

Kohrgruber, Halanek, Gröger, Winter, Rappersberger, Schmitt-Egenolf, Stingl, Maurer: "Survival, maturation, and function of CD11c- and CD11c+ peripheral blood dendritic cells are differentially regulated by cytokines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 6, pp. 3250-9, 1999 (PubMed).

Jego, Robillard, Puthier, Amiot, Accard, Pineau, Harousseau, Bataille, Pellat-Deceunynck: "Reactive plasmacytoses are expansions of plasmablasts retaining the capacity to differentiate into plasma cells." in: Blood, Vol. 94, Issue 2, pp. 701-12, 1999 (PubMed).