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CD2 Antikörper (CD2 Molecule) (Biotin)

Details für Produkt anti-CD2 Antikörper Nr. ABIN1106020, Anbieter: Anmelden zum Anzeigen
Antigen
  • CD2
  • LFA-2
  • Ly-37
  • Ly37
  • SRBC
  • T11
  • CD2R
  • LFA2
  • OX-34
  • OX34
  • CD2 molecule
  • CD2 antigen
  • Cd2 molecule
  • CD2
  • Cd2
Reaktivität
Human
568
147
123
34
25
25
18
15
14
11
10
10
6
5
4
3
2
2
Wirt
Maus
616
116
89
4
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser CD2 Antikörper ist konjugiert mit Biotin
81
77
65
20
19
19
17
17
16
14
13
13
13
13
13
11
9
9
5
5
5
5
5
4
4
3
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
642
172
169
134
125
107
102
93
90
44
13
12
10
9
8
7
4
4
4
3
2
2
2
2
1
1
1
1
1
Optionen
Hersteller
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Immunogen Human thymocytes. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells
Klon B-E2
Isotyp IgG2b
Spezifität Recognizes the Lymphocyte Function associated Antigen-2 (LFA-2), a 50 kDa protein.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Ion Exchange Chromatography.
Andere Bezeichnung CD2 (CD2 Antibody Abstract)
Hintergrund CD2 which is also known as E-rosette receptor, T11 and lymphocyte-function antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 play a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.Synonyms: Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5
Gen-ID 914
NCBI Accession NP_001758
UniProt P06729
Forschungsgebiet Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Rekonstitution Restore with 1.0 mL deionised water.
Buffer PBS containing 5 % BSA as stabilizer and 0.09 % Sodium Azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store the antibody at 2-8 °C after reconstitution.
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-CD2 Antikörper (CD2 Molecule)  (Biotin) (ABIN1106020) anti-CD2 Molecule (CD2) antibody (Biotin)
Allgemeine Veröffentlichungen Jiang, Peterlin: "Differential chromatin looping regulates CD4 expression in immature thymocytes." in: Molecular and cellular biology, Vol. 28, Issue 3, pp. 907-12, 2008 (PubMed).