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CD130/gp130 Antikörper (FITC)

IL6ST Reaktivität: Human FACS Wirt: Maus Monoclonal B-R3 FITC
Produktnummer ABIN1105854
  • Target Alle CD130/gp130 (IL6ST) Antikörper anzeigen
    CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
    Reaktivität
    • 139
    • 66
    • 56
    • 20
    • 18
    • 18
    • 17
    • 4
    • 1
    • 1
    Human
    Wirt
    • 115
    • 26
    • 4
    • 2
    • 1
    Maus
    Klonalität
    • 117
    • 31
    Monoklonal
    Konjugat
    • 53
    • 15
    • 9
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD130/gp130 Antikörper ist konjugiert mit FITC
    Applikation
    • 99
    • 39
    • 39
    • 31
    • 28
    • 26
    • 18
    • 13
    • 10
    • 9
    • 9
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Recognises the Gp130, common subunit for IL-6, IL-11, OSM, LIF, CNTF, CT-1 receptors, a 130-140 kDa protein.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Ion Exchange Chromatography
    Immunogen
    Natural soluble gp130.
    Klon
    B-R3
    Isotyp
    IgG2a
    Top Product
    Discover our top product IL6ST Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative and 5 % BSA as stabilizer
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
    Andere Bezeichnung
    CD130 / IL6ST (IL6ST Produkte)
    Synonyme
    CD130 antikoerper, CDW130 antikoerper, GP130 antikoerper, IL-6RB antikoerper, 5133400A03Rik antikoerper, AA389424 antikoerper, BB405851 antikoerper, D13Ertd699e antikoerper, gp130 antikoerper, Ac1055 antikoerper, Gp130 antikoerper, Il-6rb antikoerper, IL-6 antikoerper, interleukin 6 signal transducer antikoerper, IL6ST antikoerper, Il6st antikoerper, il6st antikoerper
    Hintergrund
    CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.Synonyms: IL-6R-beta, IL6 receptor beta, Interleukin-6 receptor subunit beta
    Gen-ID
    3572
    NCBI Accession
    NP_002175
    UniProt
    P40189
    Pathways
    JAK-STAT Signalweg, Cellular Glucan Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
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