Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PYCARD Antikörper

PYCARD Reaktivität: Human WB, IP Wirt: Maus Monoclonal 23-04-14 unconjugated
Produktnummer ABIN1105662
  • Target Alle PYCARD Antikörper anzeigen
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Reaktivität
    • 57
    • 10
    • 9
    • 1
    • 1
    • 1
    Human
    Wirt
    • 49
    • 6
    • 3
    Maus
    Klonalität
    • 47
    • 11
    Monoklonal
    Konjugat
    • 33
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PYCARD Antikörper ist unkonjugiert
    Applikation
    • 40
    • 23
    • 15
    • 14
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Spezifität
    This antibody reacts with human ASC of U937, and HL-60, but not with Jurkat, HeLa, NB4, or HPB-ALL. It does not react with mouse NIH/3T3, L5178Y, or WR19L. It does not react with rat PC12.
    Aufreinigung
    Protein A agarose
    Immunogen
    Triton X-100 insoluble fraction of retinoic acid-treated HL-60 cells
    Klon
    23-04-14
    Isotyp
    IgG1
    Top Product
    Discover our top product PYCARD Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store (in aliquots) at -20 °C.
  • Target
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Andere Bezeichnung
    CARD5 / PYCARD / ASC (PYCARD Produkte)
    Synonyme
    ASC antikoerper, CARD5 antikoerper, TMS antikoerper, TMS-1 antikoerper, TMS1 antikoerper, 9130417A21Rik antikoerper, Asc antikoerper, TNS1 antikoerper, masc antikoerper, asc1 antikoerper, zAsc antikoerper, zgc:109874 antikoerper, PYD and CARD domain containing antikoerper, PYCARD antikoerper, Pycard antikoerper, pycard antikoerper
    Hintergrund
    ASC (apoptosis-associated speck-like protein containing a CARD (caspase recruitment domain)) is a 22 kDa soluble protein, located in the cytosol of HL-60 cells. In apoptotic HL-60 cells, it is able to visualized as a speck, forming an insoluble aggregate. The C-terminal domain of this protein contains a CARD, suggesting that ASC may have proapoptotic activity in HL-60 cells. Recent data have indicated that ASC plays a role of adaptor protein linking various PAAD (Pyrin, AIM, ASC, and death domain-like) family proteins to pathways involved in NF-κB and procaspase-1 activation.Synonyms: Caspase recruitment domain-containing protein 5, PYD and CARD domain-containing protein, TMS1, Target of methylation-induced silencing 1, poptosis-associated speck-like protein containing a CARD
    Molekulargewicht
    22 kDa
    Gen-ID
    29108
    NCBI Accession
    NP_037390
    UniProt
    Q9ULZ3
    Pathways
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
Sie sind hier:
Kundenservice