SLPI Antikörper

Produktnummer ABIN1105384

Produktdetails anti-SLPI Antikörper

Target: SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLPI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Spezifität: The antibody reacts with secretory leukocyte proteinase inhibitor (SLPI, also known as antileukoprotease (ALP)).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu SLPI

Target: SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))

Andere Bezeichnung: Antileukoproteinase (ALP) (SLPI Produkte)

Synonyme: ALK1 antikoerper, ALP antikoerper, BLPI antikoerper, HUSI antikoerper, HUSI-I antikoerper, MPI antikoerper, WAP4 antikoerper, WFDC4 antikoerper, MATN4 antikoerper, SLPI antikoerper, ckpi antikoerper, secretory leukocyte peptidase inhibitor antikoerper, antileukoproteinase antikoerper, SLPI antikoerper, Slpi antikoerper, LOC102174044 antikoerper

Hintergrund: SLPI is a 11.7 kDa cationic inhibitor of neutrophil elastase and to a lesser extent of cathepsin G. It is locally produced by epithelial cells in the lung, skin and other organs, by Polymorphonuclear leukocytes (PMN) and (in mice) by macrophages. In addition to its proteinase inhibitory properties that may serve to protect against proteolytic injury, it was recently shown that SLPI also displays several other functions such as antimicrobial and anti-inflammatory activities. These appear to be independent of its ability to inhibit PMN serine proteinases. SLPI has also been demonstrated to display antibacterial and antifungal activity at concentrations in which SLPI is present in mucosal secretions including those of the lung. Another possible role for SLPI is inhibition of protein-disulphide isomerase that is considered essential for invasion of a cell by the Human Immunodeficiency Virus (HIV).Synonyms: BLPI, HUSI-1, Mucus proteinase inhibitor, Protease inhibitor WAP4, SLPI, Secretory leukocyte protease inhibitor, Seminal proteinase inhibitor, WAP four-disulfide core domain protein 4, WAP4, WFDC4

Gen-ID: 6590

NCBI Accession: NP_003055

UniProt: P03973