ALPL Antikörper (N-Term)

Produktnummer ABIN1105292

Produktdetails anti-ALPL Antikörper

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALPL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequenz: EKEKDPKYWR DQAQE

Spezifität: This antibody detects Alkaline phosphatase / ALPL at N-term. No cross reactivity with other proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide corresponding to a sequence at the N-terminal of Human ALPL (21-35)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ALPL

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Andere Bezeichnung: Alkaline Phosphatase / ALPL (ALPL Produkte)

Synonyme: ALP antikoerper, iap antikoerper, alpl antikoerper, AP-TNAP antikoerper, APTNAP antikoerper, HOPS antikoerper, TNAP antikoerper, TNSALP antikoerper, Akp-2 antikoerper, Akp2 antikoerper, PHOA antikoerper, TNS-AP antikoerper, alkaline phosphatase, liver/bone/kidney L homeolog antikoerper, alkaline phosphatase, liver/bone/kidney antikoerper, alkaline phosphatase, intestinal, gene 2 antikoerper, alkaline phosphatase, liver/bone/kidney pseudogene antikoerper, alpl.L antikoerper, ALPL antikoerper, alpi.2 antikoerper, LOC100031702 antikoerper, Alpl antikoerper

Hintergrund: Alkaline phosphatase (ALPL) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH . Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. ALPL is the alkaline phosphatase of skin fibroblasts, the tissue-nonspecific type, and that it is active toward millimolar concentrations of the putative natural substrates phosphoethanolamine (PEA) and pyridoxal-5-prime-phosphate (PLP). ALPL gene exists in single copy in the haploid genome and is composed of 12 exons distributed over more than 50 kb.Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.Synonyms: AP-TNAP, Alkaline phosphatase, Alkaline phosphatase liver/bone/kidney isozyme, TNSALP, tissue-nonspecific isozyme

Gen-ID: 249

NCBI Accession: NP_000469

UniProt: P05186