ADAMTS4 Antikörper (C-Term)

Produktnummer ABIN1105251

Produktdetails anti-ADAMTS4 Antikörper

Target: ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Bindungsspezifität: C-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAMTS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects ADAMTS4 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Mouse, rat

Aufreinigung: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of mouse ADAMTS4 .Remarks: Sequence is different to the related rat sequence by three amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu ADAMTS4

Target: ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Andere Bezeichnung: ADAMTS4 (ADAMTS4 Produkte)

Synonyme: 3830423K05 antikoerper, ADAM-TS4 antikoerper, ADAMTS-2 antikoerper, ADMP-1 antikoerper, mKIAA0688 antikoerper, ADAMTS-4 antikoerper, ADAMTS4 antikoerper, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif 4 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif, 4 antikoerper, Adamts4 antikoerper, ADAMTS4 antikoerper

Hintergrund: ADAM metallopeptidase with thrombospondin type 1 motif, 4, also known as ADAMTS4, is a human gene. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS is a novel family of extracellular proteases found in both mammals and invertebrates. Members of the family may be distinguished from the ADAM (adisintegrin and metalloprotease) family members based on the multiple copies of thrombospondin 1-like repeats they carry. Pratta et al. (2003) concluded that ADAMTS4 is constitutively produced in monolayer chondrocytes, capsular fibroblasts, and cartilage, and that stimulation by interleukin-1 results in aggrecanase activation. Thus, the activator could be a potential target by which to control aggrecanase-mediated degradation in arthritic diseases.Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS4, ADAMTS-4, ADMP-1, ADMP1, Aggrecanase-1, KIAA0688

Gen-ID: 9507

NCBI Accession: NP_005090

UniProt: O75173