Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) Antikörper

Antigen: Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1)

Synonyme: HDL, 11-DH, HSD11, HSD11B, HSD11L, SDR26C1, MGC13539, 11-beta-HSD1, HSD11B1, hsd11, hsd11b, MGC64545, Hsd11b1

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN110226

Produktbeschreibung

Weitere Bezeichnung: 11beta-Hydroxysteroid Dehydrogenase (Type 1)

Immunogen: human 11beta-HSD1 amino acids

Beschreibung: 11beta-Hydroxysteroid dehydrogenase (Type 1) (11beta-HSD1) catalyzes the conversion of inactive cortisone to active cortisol in adipose tissue. mRNA and protein for this enzyme have been detected in a wide range of tissues including liver, kidney, testis, lung, heart, and colon. The enzyme's expression is developmentally regulated, suggesting its importance in regulation of glucocorticoid action during embryonic development. Over-expression of 11beta-HSD1 results in visceral obesity and metabolic syndrome including insulin-resistant diabetes, hyperlipidemia, and hyperphagia. Cayman Chemical's 11beta-HSD1 Polyclonal Antibody can be used for WB and IHC (formalin-fixed paraffin-embedded sections) analysis for 11beta-HSD1 on samples of human, murine, and rat origin. Other applications for use of this antibody have not yet been tested. The antibody detects a 32 kDa protein in human, murine, and rat liver samples by WB analysis.

Spezifität: Human 11beta-HSD1: +, Murine 11beta-HSD1: +, Rat 11beta-HSD1: +

Anwendungen

Reinheit: >98%

Buffer: Peptide affinity-purified IgG

Lagerung: 1 year

Forschungsgebiet: Enzyme

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) antibody