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ATP7B Antikörper (AA 3-21)

ATP7B Reaktivität: Human WB, IHC, IP, IF/ICC Wirt: Maus Monoclonal S62-29 unconjugated
Produktnummer ABIN1098199
  • Target Alle ATP7B Antikörper anzeigen
    ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
    Bindungsspezifität
    • 15
    • 13
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-21
    Reaktivität
    • 37
    • 26
    • 21
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 39
    • 21
    Maus
    Klonalität
    • 39
    • 21
    Monoklonal
    Konjugat
    • 23
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATP7B Antikörper ist unkonjugiert
    Applikation
    • 41
    • 22
    • 18
    • 16
    • 13
    • 13
    • 13
    • 9
    • 9
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC)
    Verwendungszweck
    Anti-Copper-Transporting ATPase2 Mouse Monoclonal Antibody
    Spezifität
    This antibody recognizes human, mouse, and rat Copper-Transporting ATPase2.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein G affinity chromatography.
    Immunogen
    Synthetic peptide correspond- ing to aa 3-21 (cytoplasmic N-terminus) of human Copper-Transporting ATPase2. (accession no. NP_000044.2).
    Klon
    S62-29
    Isotyp
    IgG1
    Top Product
    Discover our top product ATP7B Primärantikörper
  • Applikationshinweise
    Immunoblotting: use at 1-2 μg/mL. A band of ~160 kDa is detected.
    Immunohistochemistry: use at 1-5 μg/mL.
    These are recommended concentrations.
    Enduser should determine optimal concentrations for their applications.
    Positive control: rat brain membranes.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Rekonstitution
    Dilute in PBS or medium that is identical to that used in the assay system.
    Konzentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    This product is stable for at least 1 year at -20°C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.
  • Target
    ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
    Andere Bezeichnung
    Copper-Transporting ATPase2 (ATP7B Produkte)
    Synonyme
    PWD antikoerper, WC1 antikoerper, WD antikoerper, WND antikoerper, Atp7a antikoerper, tx antikoerper, Hts antikoerper, PINA antikoerper, Wd antikoerper, ATP7B antikoerper, ATPase copper transporting beta antikoerper, ATPase, Cu++ transporting, beta polypeptide antikoerper, ATPase, Cu++ transporting, beta polypeptide (Wilson disease) antikoerper, copper-transporting ATPase 2 antikoerper, ATP7B antikoerper, Atp7b antikoerper, atp7b antikoerper, LOC592143 antikoerper
    Hintergrund
    P-type Cu(+) transporter,The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from cells. ATP7b (also known as Copper-Transporting ATPase2) transports copper in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene: A is found in the liver, kidney and brain, the shorter form B is found in brain, and the third isoform, known as WND/140KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.
    UniProt
    B7ZLR4
    Pathways
    Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
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