Osteopontin Antikörper (AA 167-314)

Produktnummer ABIN1098149

Produktdetails anti-Osteopontin Antikörper

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Bindungsspezifität: AA 167-314

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Osteopontin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. coli.

Klon: 7C5H12

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Osteopontin Antikörper (ABIN1098149)

Liersch, Gerss, Schliemann, Bayer, Schwöppe, Biermann, Appelmann, Kessler, Löwenberg, Büchner, Hiddemann, Müller-Tidow, Berdel, Mesters: "Osteopontin is a prognostic factor for survival of acute myeloid leukemia patients." in: Blood, Vol. 119, Issue 22, pp. 5215-20, (2012) (PubMed).

Wang, Wang, Tang: "Osteopontin expression in nasopharyngeal carcinoma: its relevance to the clinical stage of the disease." in: Journal of cancer research and therapeutics, Vol. 7, Issue 2, pp. 138-42, (2011) (PubMed).

Details zu Osteopontin

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Andere Bezeichnung: SPP1 (SPP1 Produkte)

Synonyme: BNSP antikoerper, BSPI antikoerper, ETA-1 antikoerper, OPN antikoerper, 2AR antikoerper, Apl-1 antikoerper, Bsp antikoerper, Eta antikoerper, OP antikoerper, Opn antikoerper, Opnl antikoerper, Ric antikoerper, Spp-1 antikoerper, OSP antikoerper, zgc:111821 antikoerper, secreted phosphoprotein 1 antikoerper, SPP1 antikoerper, Spp1 antikoerper, spp1 antikoerper

Hintergrund:

Description: The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. , , ,

Aliases: OPN, BNSP, BSPI, ETA-1

Molekulargewicht: 35.4 kDa

Gen-ID: 6696

HGNC: 6696

Pathways: Regulation of Cell Size