Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

KEAP1 Antikörper (AA 380-624)

KEAP1 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 7G4B10 unconjugated
Produktnummer ABIN1098141
  • Target Alle KEAP1 Antikörper anzeigen
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    Bindungsspezifität
    • 21
    • 15
    • 15
    • 15
    • 10
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 380-624
    Reaktivität
    • 88
    • 57
    • 29
    • 20
    • 18
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    Human
    Wirt
    • 91
    • 6
    • 1
    Maus
    Klonalität
    • 90
    • 8
    Monoklonal
    Konjugat
    • 43
    • 10
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser KEAP1 Antikörper ist unkonjugiert
    Applikation
    • 85
    • 49
    • 32
    • 26
    • 26
    • 16
    • 10
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human KEAP1 (AA: 380-624 ) expressed in E. coli.
    Klon
    7G4B10
    Isotyp
    IgG1
    Top Product
    Discover our top product KEAP1 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Muscarella, Barbano, DAngelo, Copetti, Coco, Balsamo, la Torre, Notarangelo, Troiano, Parisi, Icolaro, Catapano, Valori, Pellegrini, Merla, Carella, Fazio, Parrella: "Regulation of KEAP1 expression by promoter methylation in malignant gliomas and association with patient's outcome." in: Epigenetics, Vol. 6, Issue 3, pp. 317-25, (2011) (PubMed).

    Niture, Jaiswal: "INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis." in: Cell death and differentiation, Vol. 18, Issue 3, pp. 439-51, (2011) (PubMed).

  • Target
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    Andere Bezeichnung
    KEAP1 (KEAP1 Produkte)
    Synonyme
    INrf2 antikoerper, KLHL19 antikoerper, INRF2 antikoerper, mKIAA0132 antikoerper, Inrf2 antikoerper, fb36f11 antikoerper, keap1 antikoerper, wu:fb36f11 antikoerper, KEAP1 antikoerper, klhl19 antikoerper, zgc:171654 antikoerper, kelch like ECH associated protein 1 antikoerper, kelch-like ECH-associated protein 1 antikoerper, Kelch-like ECH-associated protein 1 antikoerper, kelch-like ECH-associated protein 1a antikoerper, kelch like ECH associated protein 1 L homeolog antikoerper, kelch-like ECH-associated protein 1b antikoerper, KEAP1 antikoerper, Keap1 antikoerper, keap1a antikoerper, keap1 antikoerper, keap1.L antikoerper, keap1b antikoerper
    Hintergrund

    Description: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. , ,

    Aliases: INrf2, KLHL19

    Molekulargewicht
    69.7 kDa
    Gen-ID
    9817
    HGNC
    9817
    Pathways
    Maintenance of Protein Location
Sie sind hier:
Kundenservice