LMO2 Antikörper (AA 1-158)

Produktnummer ABIN1098128

Produktdetails anti-LMO2 Antikörper

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Bindungsspezifität: AA 1-158

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LMO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human LMO2 (AA: 1-158) expressed in E. coli.

Klon: 4D8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: Propose dilution 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-LMO2 Antikörper (ABIN1098128)

Cubedo, Maurin, Jiang, Lossos, Wright: "PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." in: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, (2011) (PubMed).

Baecklund, Backlin, Mansouri, Klareskog, Askling, Iliadou, Enblad, Lossos, Natkunam, Rosenquist: "LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma." in: Leukemia & lymphoma, Vol. 52, Issue 6, pp. 1146-9, (2011) (PubMed).

Details zu LMO2

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Andere Bezeichnung: LMO2 (LMO2 Produkte)

Synonyme: Rbtn-2 antikoerper, Rbtn2 antikoerper, Rhom-2 antikoerper, Ttg2 antikoerper, RBTN2 antikoerper, RBTNL1 antikoerper, RHOM2 antikoerper, TTG2 antikoerper, wu:fc83a08 antikoerper, zgc:111930 antikoerper, LMO-2 antikoerper, lmo2-A antikoerper, xlmo2 antikoerper, rhombotin-2 antikoerper, LIM domain only 2 antikoerper, LIM domain only 2 (rhombotin-like 1) antikoerper, LIM domain only 2 S homeolog antikoerper, lmo2 antikoerper, LMO2 antikoerper, Lmo2 antikoerper, lmo2.S antikoerper

Hintergrund:

Description: LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms. , ,

Aliases: TTG2, RBTN2, RHOM2, RBTNL1

Molekulargewicht: 18.4 kDa

Gen-ID: 4005

HGNC: 4005

Pathways: Chromatin Binding