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NEDD9 Antikörper (AA 82-398)

NEDD9 Reaktivität: Human, Ratte, Maus WB, IF, IP, ICC, FACS, IHC (fro) Wirt: Maus Monoclonal 2G9 unconjugated
Produktnummer ABIN7278755
  • Target Alle NEDD9 Antikörper anzeigen
    NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))
    Bindungsspezifität
    • 9
    • 9
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 82-398
    Reaktivität
    • 46
    • 11
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 39
    • 6
    • 1
    Maus
    Klonalität
    • 41
    • 5
    Monoklonal
    Konjugat
    • 24
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser NEDD9 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 18
    • 14
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    Does not recognize p130 Cas. Not tested on Sin1. This antibody mostly detects HEF1 localized at the focal adhesion sites
    Aufreinigung
    Protein G
    Immunogen
    Fusion protein, corresponding to amino acids 82-398 of Human HEF1.
    Klon
    2G9
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product NEDD9 Primärantikörper
  • Applikationshinweise
    Optimal antibody dilution should be determined by titration, however as a guideline try, WB: 1/2000 - 1/6000. Predicted molecular weight: 93 kDa. IP: 1/1000. ICC/IF: Use at an assay dependent dilution. PubMed: 19376971 IHC-Fr: Use at an assay dependent dilution. PubMed: 19464348 Flow Cyt: Use 1 μg for 106 cells
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Purified antibody containing PBS 0.1 % sodium azide,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Tomkiewicz, Herry, Bui, Métayer, Bourdeloux, Barouki, Coumoul: "The aryl hydrocarbon receptor regulates focal adhesion sites through a non-genomic FAK/Src pathway." in: Oncogene, Vol. 32, Issue 14, pp. 1811-20, (2013) (PubMed).

    Zhong, Baquiran, Bonakdar, Lees, Ching, Pugacheva, Fabry, ONeill: "NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration." in: PLoS ONE, Vol. 7, Issue 4, pp. e35058, (2012) (PubMed).

    ONeill, Golemis: "Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics." in: Molecular and cellular biology, Vol. 21, Issue 15, pp. 5094-108, (2001) (PubMed).

  • Target
    NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))
    Andere Bezeichnung
    HEF1 (NEDD9 Produkte)
    Synonyme
    NEDD9 antikoerper, CAS-L antikoerper, CAS2 antikoerper, CASL antikoerper, CASS2 antikoerper, HEF1 antikoerper, Cas-L antikoerper, CasL antikoerper, E230025G09Rik antikoerper, neural precursor cell expressed, developmentally down-regulated 9 antikoerper, neural precursor cell expressed, developmentally down-regulated gene 9 antikoerper, NEDD9 antikoerper, Nedd9 antikoerper
    Hintergrund
    Synonyms:
    CAS L antibody,Cas like docking antibody,CASL antibody,Crk associated substrate related proteinantibody,dJ49G10.2 antibody,dJ761I2.1 antibody,Enhancer of filamentation 1 antibody,HEF 1 antibody,NEDD 9antibody,NEDD9 antibody,NEDD9 protein antibody,Neural cell expressed developmentally down regulated 9antibody,Neural precursor cell expressed developmentally down regulated 9 antibody,NY REN 12 antigenantibody,p105 antibody,Protein NEDD9 antibody
    Gen-ID
    4739, 18003, 291044
    OMIM
    602265
    UniProt
    O35177
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