Ubiqutin Antikörper

Antigen: Ubiqutin

Klonalität: Monoklonal (FPM1)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (IHC)

Produktnummer: ABIN108023

Produktbeschreibung

Immunogen: BALB/C mice were immunized with purified human ubiquitin.

Format: Supernatant

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: FPM1

Spezifität: This antibody recognizes neurofibrillary tangles in Alzheimer

Anwendungen

Applikationshinweise: Titer/Working Dilution: This antibody may be diluted to a titer of 1:10-1:25 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Suitable for formalin/paraffin tissues. Positive Control: Alzheimer brain. Cellular localization: Nuclear, cytoplasmic and cell membrane

Konzentration: 100ug/ml approximately

Buffer: This antibody is supplied as tissue culture supernatant containing azide as the preservative.

Lagerung: Store the antibody 2-8o c. Do not use it beyond the expiration date stated on the label.

Forschungsgebiet: Proteasen, Aminosäuren

Beschränkungen: Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Publikationen

Publikationen: Lennox, Lowe, Morrell et al.: "Anti-ubiquitin immunocytochemistry is more sensitive than conventional techniques in the detection of diffuse Lewy body disease." in: Journal of neurology, neurosurgery, and psychiatry, Vol. 52, Issue 1, pp. 67-71, 1989 (PubMed).

Lowe, Lennox, Jefferson et al.: "A filamentous inclusion body within anterior horn neurones in motor neurone disease defined by immunocytochemical localisation of ubiquitin." in: Neuroscience letters, Vol. 94, Issue 1-2, pp. 203-10, 1989 (PubMed).