MECR Antikörper (C-Term)

Produktnummer ABIN1077414

Produktdetails anti-MECR Antikörper

Target: MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MECR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: At least two isoforms of MECR are known to exist, this antibody will detect both isoforms.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal MECR antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MECR.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: MECR antibody can be used for detection of MECR by Western blot at 1 - 2 μg/mL.

Kommentare:

(CT) Mitochondrial trans-2-enoyl-CoA reductase

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: MECR antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu MECR

Target: MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))

Andere Bezeichnung: MECR (MECR Produkte)

Synonyme: CGI-63 antikoerper, FASN2B antikoerper, NRBF1 antikoerper, AI195831 antikoerper, Nrbf1 antikoerper, mitochondrial trans-2-enoyl-CoA reductase antikoerper, MECR antikoerper, Mecr antikoerper

Hintergrund: The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.
Synonyms: Mitochondrial trans-2-enoyl-CoA reductase, nuclear receptor-binding factor 1, NRBF1, CGI-63, FASN2B

Molekulargewicht: 41 kDa (calculated)

Gen-ID: 51102

NCBI Accession: NP_057095