TCR Antikörper

Antigen: TCR

Klonalität: Monoklonal (UC3-10A6)

Wirt: Armenischer Hamster

Reaktivität: Maus

Applikation: Durchflusszytometrie (FACS), Immunpräzipitation (IP)

Produktnummer: ABIN107292

Produktbeschreibung

Immunogen: Purified Recombinant Mouse TCR (>98%) Formulation This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.

Isotyp: IgG  (Passende Sekundärantikörper)

Klon: UC3-10A6

Beschreibung: The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an a and chain in 95% of T cells, while 5% of T cells have TCRs consisting of ? and d chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.

Spezifität: This antibody reacts with V? 2 T-Cell Receptor (TCR)-bearing T lymphocytes. Antigen Distribution: V? 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of ?d TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung.

Anwendungen

Applikationshinweise: FC, IP. Each Investigator should determine their own optimal working dilution for specific applications.

Reinigung: Purified

Buffer: This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Stability This antibody is stable when stored at 2-8C. Do not freeze. Reported Applications FC

Lagerung: This antibody is stable when stored at 2-8°C. Do not freeze.

Forschungsgebiet: Immunologie, Rezeptoren

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Murdoch, Lloyd: "Resolution of Allergic Airway Inflammation and Airway Hyperreactivity is Mediated by IL-17 Producing {gamma}{delta}T Cells." in: American journal of respiratory and critical care medicine, 2010 (PubMed).