Neurofilament, Heavy Polypeptide 200kDa (NEFH) (200 kD) Antikörper

Antigen: Neurofilament, Heavy Polypeptide 200kDa (NEFH)

Synonyme: NFH, NEFH, nfh

Epitope: 200 kD

Klonalität: Monoklonal (RT97)

Wirt: Maus

Reaktivität: Human, Ratte (Rattus)

Applikation: Immunhistochemie (IHC)

Produktnummer: ABIN104615

Produktbeschreibung

Weitere Bezeichnung: Neurofilament H (200 kD)

Immunogen: Triton x 100 insoluble rat brain protein.

Format: Supernatant

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: RT97

Spezifität: This antibody stains strongly with human neurofilaments of 200 kD. It stains neuromas, gangliomas, neuroblastomas and medulloblastomas. It also stains neuronal processes in brain and other nervous tissues. This antibody is useful to detect paragangliomas, phaeochromocytomas and other tumors of neuroectodermal origin.

Anwendungen

Applikationshinweise: Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Suitable for formalin/paraffin tissues. Positive Control: Brain. Cellular localization: Cytoplasmic

Konzentration: 100ug/ml approximately

Buffer: This antibody is supplied as tissue culture supernatant containing sodium azide as preservative.

Lagerung: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Forschungsgebiet: Zytoskelett, Zell-/Gewebemarker

Beschränkungen: Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Publikationen

Publikationen: Anderton, Breinburg, Downes et al.: "Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants." in: Nature, Vol. 298, Issue 5869, pp. 84-6, 1982 (PubMed).