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Interleukin 17a Antikörper (HRP)

IL17A Reaktivität: Maus, Ratte ELISA, WB Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1043841
  • Target Alle Interleukin 17a (IL17A) Antikörper anzeigen
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    Reaktivität
    • 103
    • 53
    • 18
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    Maus, Ratte
    Wirt
    • 61
    • 52
    • 29
    • 8
    • 3
    Kaninchen
    Klonalität
    • 81
    • 71
    • 1
    Polyklonal
    Konjugat
    • 69
    • 24
    • 15
    • 11
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Interleukin 17a Antikörper ist konjugiert mit HRP
    Applikation
    • 73
    • 63
    • 49
    • 15
    • 12
    • 12
    • 12
    • 11
    • 10
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Spezifität
    This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant rat IL17-A in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
    Produktmerkmale
    Rat IL17-A (also known as Interleukin-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8) is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Rat IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58% identity between the amino acid sequence of human and rat IL-17A.
    Aufreinigung
    purified
    Immunogen
    This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant rat IL17-A protein.
    Immunogen Type: Recombinant Protein
    Isotyp
    IgG
    Top Product
    Discover our top product IL17A Primärantikörper
  • Applikationshinweise
    This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 30.0 kDa in size corresponding to rat IL17-A protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
    Kommentare

    Gene Name: IL17A

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
    Konservierungsmittel
    Gentamicin sulfate
    Handhabung
    Do NOT add Sodium Azide!
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Haltbarkeit
    12 months
  • Rouvier, Luciani, Mattéi, Denizot, Golstein: "CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 12, pp. 5445-56, (1993) (PubMed).

  • Target
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    Andere Bezeichnung
    IL-17A (IL17A Produkte)
    Synonyme
    CTLA8 antikoerper, IL-17 antikoerper, IL-17A antikoerper, IL17 antikoerper, Ctla-8 antikoerper, Ctla8 antikoerper, Il17 antikoerper, ChIL-17 antikoerper, IL-17F antikoerper, IL17A antikoerper, CTLA-8 antikoerper, interleukin 17A antikoerper, IL17A antikoerper, Il17a antikoerper
    Hintergrund
    Rat IL17-A (also known as Interleukin-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8) is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Rat IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58% identity between the amino acid sequence of human and rat IL-17A.
    Synonyms: Interleukin-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8, HRP
    Gen-ID
    301289
    UniProt
    Q61453
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