MIC2 Gene Protein Antikörper

Antigen: MIC2 Gene Protein

Klonalität: Monoklonal (12E7)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN104203

Produktbeschreibung

Immunogen: BALB/C mice were injected with acute lymphocytic leukemia T-cells.

Format: Supernatant (prediluted)

Isotyp: IgG1 kappa  (Passende Sekundärantikörper)

Klon: 12E7

Spezifität: This antibody reacts with the MIC2 gene products expressed on the cell membrane of lymphocytes, cortical thymocytes, Langerhans' islet cells, granulosa cells of the ovary and Sertoli's cells of the testis. This antibody reacts strongly with Ewing's Sarcoma and peripheral neuroectodermal tumors.

Anwendungen

Applikationshinweise: Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Suitable for formalin/paraffin tissues. Positive Control: Tonsil. Cellular localization: Cell membrane

Konzentration: 1 to 4 ug/ml

Buffer: This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required.

Lagerung: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Beschränkungen: Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Publikationen

Publikationen: in:

Fellinger, Garin-Chesa, Glasser et al.: "Comparison of cell surface antigen HBA71 (p30/32MIC2), neuron-specific enolase, and vimentin in the immunohistochemical analysis of Ewing's sarcoma of bone." in: The American journal of surgical pathology, Vol. 16, Issue 8, pp. 746-55, 1992 (PubMed).

Ambros, Ambros, Strehl et al.: "MIC2 is a specific marker for Ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of Ewing's sarcoma and peripheral primitive neuroectodermal tumors from MIC2 expression and specific chromosome aberration." in: Cancer, Vol. 67, Issue 7, pp. 1886-93, 1991 (PubMed).