Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) Antikörper

Details zu Produkt Nr. ABIN1003416, Anbieter: Anmelden zum Anzeigen
Antigen
  • APBA1
  • 6430513E09Rik
  • Lin-10
  • Mint
  • Mint1
  • Urop11
  • X11
  • X11alpha
  • D9S411E
  • LIN10
  • MINT1
  • X11A
  • X11ALPHA
  • amyloid beta precursor protein binding family A member 1
  • amyloid beta (A4) precursor protein-binding, family A, member 1b
  • ketopantoate reductase
  • 2-dehydropantoate 2-reductase
  • amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)
  • amyloid beta (A4) precursor protein-binding, family A, member 1
  • amyloid beta (A4) precursor protein binding, family A, member 1
  • APBA1
  • apba1b
  • apbA1
  • apba1
  • Apba1
Reaktivität
Human, Maus, Ratte (Rattus)
69
47
40
2
2
1
1
1
1
1
1
1
1
Wirt
Kaninchen
60
16
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
55
39
15
13
10
6
3
2
Optionen
Hersteller
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Immunogen UROP11 antibody was raised in rabbits against a 12 amino acid peptide near the center of the mouse UROP11.
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN1004499.
Isotyp IgG
Reinigung Affinity chromatography purified via peptide column.
Andere Bezeichnung UROP11 (Upregulated obese product 11) (APBA1 Antibody Abstract)
Hintergrund Upregulated obese product 11 (UROP11) was isolated from subtractive library for mouse hypothalamus. It is detected in numerous tissues and is upregulated in the hypothalamus and adipocytes in obese mice. UROP11 is also observed in human neural and lymphoid tissues, its expression appears to be regulated by the level of lymphoid activation. Urop11 expression is strongly upregulated both in vivo in mouse hypothalamus and in vitro in mouse neural cell lines after treatment with leptin, indicating Urop11 is a target of leptin activity and thus may play a role in obesity. Despite its predicted molecular weight, UROP11 often migrates at a much higher apparent size in SDS-PAGE.
Pathways Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Applikationshinweise UROP11 antibody can be used for detection of UROP11 by Western blot at 1 – 2 µg/ml. (Optimal dilution should be determined by user). Antibody can also be used for ELISA and might be suited for other applications not tested so far.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer Antibody is supplied in PBS containing 0.02% sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
Lagerung 4 °C
Haltbarkeit 12 months
Produkt verwendet in: Verlaeten, Casery, Cavagna, Naville, Giraudon, Belin, Begeot, Bernard: "Identification of Urop11, a novel leptin-modulated gene that is upregulated in the hypothalamus of mice with virus-induced obesity." in: Journal of molecular endocrinology, Vol. 38, Issue 1-2, pp. 3-17, 2007 (PubMed).

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