Prolactin-Induced Protein (PIP) Antikörper

Antigen: Prolactin-Induced Protein (PIP)

Klonalität: Monoklonal (23A3)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN100124

Produktbeschreibung

Weitere Bezeichnung: Gross Cystic Disease Fluid Protein-15 (GCDFP15)

Immunogen: Recombinant protein encoding the excreted domain of human GCDFP-15.

Format: Supernatant (prediluted)

Isotyp: IgG2a kappa  (Passende Sekundärantikörper)

Klon: 23A3

Spezifität: This antibody is specific to 15 kD monomer protein called Gross Cystic Disease Fluid Protein-15 (GCDFP-15). Gross cystic disease of the breast is benign premenopausal disorder in which cysts are predominant. These cysts appear to be formed from excessive apocrine cystic secretions, one of which is GCDFP-15. This antibody can be used in for the staining of breast carcinoma, salivary duct carcinoma and apocrine epithelia.

Anwendungen

Applikationshinweise: Staining Protocol: We suggest an incubation period of 60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM Citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Skin. Cellular localization: Cytoplasmic

Konzentration: 1 to 4 ug/ml

Buffer: This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required.

Lagerung: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Beschränkungen: Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Publikationen

Publikationen: Viacava, Naccarato, Bevilacqua: "Spectrum of GCDFP-15 expression in human fetal and adult normal tissues." in: Virchows Archiv : an international journal of pathology, Vol. 432, Issue 3, pp. 255-60, 1998 (PubMed).

Hall, Clements, Birrell et al.: "Prostate-specific antigen and gross cystic disease fluid protein-15 are co-expressed in androgen receptor-positive breast tumours." in: British journal of cancer, Vol. 78, Issue 3, pp. 360-5, 1998 (PubMed).