anti-CRTC2 (CRTC2) Antikörper

Bezeichnung:
anti-CREB Regulated Transcription Coactivator 2 Antikörper (CRTC2)
Auf www.antikoerper-online.de finden Sie aktuell 178 CREB Regulated Transcription Coactivator 2 (CRTC2) Antikörper von 23 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CRTC2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 197 CRTC2 Produkte verfügbar.
Synonyme:
4632407F12Rik, CRTC2, mTORC2, RGD1308903, TORC-2, Torc2

Meistgesuchte Reaktivitäten zu anti-CRTC2 (CRTC2) Antikörper

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anti-Human CRTC2 Antikörper:

anti-Mouse (Murine) CRTC2 Antikörper:

anti-Rat (Rattus) CRTC2 Antikörper:

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Am meisten referenzierte anti-CRTC2 Antikörper

  1. Human Polyclonal CRTC2 Primary Antibody für EIA, WB - ABIN493522 : Koo, Flechner, Qi, Zhang, Screaton, Jeffries, Hedrick, Xu, Boussouar, Brindle, Takemori, Montminy: The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. in Nature 2005 (PubMed)
    Zeige alle 6 Referenzen für 493522

  2. Human Monoclonal CRTC2 Primary Antibody für ICC, FACS - ABIN969067 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)
    Zeige alle 3 Referenzen für 969067

  3. Human Polyclonal CRTC2 Primary Antibody für WB - ABIN658088 : Nakatsu, Sakoda, Kushiyama, Ono, Fujishiro, Horike, Yoneda, Ohno, Tsuchiya, Kamata, Tahara, Isobe, Nishimura, Katagiri, Oka, Fukushima, Takahashi, Kurihara, Uchida, Asano: Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing cAMP-responsive element transcriptional activity. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 3 Referenzen für 658088

  4. Human Polyclonal CRTC2 Primary Antibody für IHC (p), WB - ABIN658242 : Kaizuka, Hara, Oshiro, Kikkawa, Yonezawa, Takehana, Iemura, Natsume, Mizushima: Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 3 Referenzen für 658242

  5. Human Monoclonal CRTC2 Primary Antibody für EIA, FACS - ABIN1106840 : Peng, Xie, Lu, Fan, Wang: Synthesis, photoelectric properties and photocatalytic activity of the Fe2O3/TiO2 heterogeneous photocatalysts. in Physical chemistry chemical physics : PCCP 2010 (PubMed)
    Zeige alle 2 Referenzen für 1106840

  6. Human Polyclonal CRTC2 Primary Antibody für ICC, IF - ABIN256688 : Jeanneteau, Lambert, Ismaili, Bath, Lee, Garabedian, Chao: BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Zeige alle 2 Referenzen für 256688

  7. Human Polyclonal CRTC2 Primary Antibody für IF (p), IHC (p) - ABIN745988 : Tian, Zhao, Sun, Zhi, Cheng, Zhou, Hu: CRTC2 enhances HBV transcription and replication by inducing PGC1? expression. in Virology journal 2014 (PubMed)
    Zeige alle 2 Referenzen für 745988

  8. Human Polyclonal CRTC2 Primary Antibody für ICC, IF - ABIN151246 : Liu, Coello, Grinevich, Aguilera: Involvement of transducer of regulated cAMP response element-binding protein activity on corticotropin releasing hormone transcription. in Endocrinology 2010 (PubMed)

Weitere Antikörper gegen CRTC2 Interaktionspartner

Human CREB Regulated Transcription Coactivator 2 (CRTC2) Interaktionspartner

  1. CRTC2 polymorphism as a risk factor for the incidence of metabolic syndrome in transplant recipients after solid organ transplantation.

  2. CRTC2 strongly enhances GR-induced transcriptional activity of glucocorticoid-responsive genes.

  3. Our results establish a role for CRTC2 as a lymphoma tumor suppressor gene

  4. the high expression of CRTC2 and PROM1 may play an important role in the occurrence and hereditary, and also advance the potential pathways that integrate genetic variants in the development of NSCLC.

  5. The data from the current study demonstrated novel PROM1 and CRTC2 mutations, which could promote lung cancer development.

  6. These results clearly indicate that non-phosphorylated CRTC2 strongly enhances hepatitis b virus biosynthesis through inducing PGC1alpha expression.

  7. Phosphorylation of CRTC2 at its AMPK (zeige PRKAA1 Antikörper) target site, Ser (zeige SIGLEC1 Antikörper) 171, dictated its subcellular localization, and the activation of aromatase (zeige CYP19A1 Antikörper) PII in preadipocytes.

  8. CRTC2 enhances CREB (zeige CREB1 Antikörper) phosphorylation through an association with the protein arginine methyltransferase 5 (PRMT5 (zeige PRMT5 Antikörper)).

  9. Mechanism of CREB (zeige CREB1 Antikörper) recognition and coactivation by the CREB (zeige CREB1 Antikörper)-regulated transcriptional coactivator CRTC2

  10. The lipogenic effects of GIP (zeige GIP Antikörper) in the presence of insulin (zeige INS Antikörper) are therefore at least partially mediated by upregulation of adipocyte LPL (zeige LCP1 Antikörper) gene transcription through a pathway involving PI3-K (zeige PIK3CA Antikörper)/PKB (zeige AKT1 Antikörper)/AMPK (zeige PRKAA1 Antikörper)-dependent CREB (zeige CREB1 Antikörper)/TORC2 activation.

Mouse (Murine) CREB Regulated Transcription Coactivator 2 (CRTC2) Interaktionspartner

  1. CRTC2 play a role in hepatic cholesterol synthesis through SREBP-2 (zeige SREBF2 Antikörper).

  2. Catecholaminergic deletion of Rictor (zeige RICTOR Antikörper) increases water, sucrose, and morphine intake but not preference in a two-bottle choice assay in stress-naive mice, and these effects are maintained after stress. Ventral Tegmental Area-specific knockout of Rictor (zeige RICTOR Antikörper) increases water and sucrose intake after physical CSDS, but does not alter consummatory behavior in the absence of stress.

  3. Three mouse CRTCs (Crtc1 (zeige CRTC1 Antikörper), Crtc2 and Crtc3 (zeige CRTC3 Antikörper)) exhibit distinct patterns of 14-3-3 (zeige YWHAQ Antikörper) binding at three conserved sites corresponding to S70, S171 (zeige NUMB Antikörper), and S275 (in CRTC2).

  4. the protein expression of adipose tissue CRTC 2 was reduced in mice with a combined application of change to general diet and exercise. In addition, while the protein expressions of lipase (zeige LIPG Antikörper) ATGL (zeige PNPLA2 Antikörper) and HSL (zeige LIPE Antikörper) were reduced in the mice fed with the high fat diet continually after obesity was induced

  5. CRTC2 promotes Th17 cell differentiation via stimulation of IL-17A (zeige IL17A Antikörper) and IL-17F (zeige IL17F Antikörper) expression by binding to CREB (zeige CREB1 Antikörper) over both promoters. CRTC2-mutant mice have decreased Th17 cells, and they are protected from experimental autoimmune encephalitis.

  6. chronic increases in CRTC2 activity in the liver are indeed sufficient to promote hepatic insulin (zeige INS Antikörper) resistance and to disrupt glucose homeostasis

  7. cAMP, SIK (zeige SIK1 Antikörper) and CRTC mediate StAR expression through activation of individual StAR gene loci.

  8. RICTOR (zeige RICTOR Antikörper)/mTORC2 is important for interactions between vasculature, adipocytes, and brain to tune physiological outcomes, such as blood pressure and locomotor activity.

  9. CREB regulated transcription coactivator 2 (CRTC2) functions as a mediator of mTOR (zeige FRAP1 Antikörper) signalling to modulate COPII-dependent SREBP1 (zeige SREBF1 Antikörper) processing

  10. Translational activation of CREB (zeige CREB1 Antikörper) is caused by elevated phospho-elF2alpha (zeige EIF2S1 Antikörper).

CRTC2 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5.

Alternative names and synonyms associated with CRTC2

  • CREB regulated transcription coactivator 2 (CRTC2) Antikörper
  • CREB regulated transcription coactivator 2 (LOC100358960) Antikörper
  • CREB regulated transcription coactivator 2 (Crtc2) Antikörper
  • 4632407F12Rik Antikörper
  • CRTC2 Antikörper
  • mTORC2 Antikörper
  • RGD1308903 Antikörper
  • TORC-2 Antikörper
  • Torc2 Antikörper

Bezeichner auf Proteinebene für CRTC2

CREB regulated transcription coactivator 2 , CREB-regulated transcription coactivator 2 , CREB-regulated transcription coactivator 2-like , transducer of regulated cAMP response element-binding protein (CREB) 2 , TORC-2 , transducer of CREB protein 2 , transducer of regulated cAMP response element-binding protein 2

GENE ID SPEZIES
612305 Canis lupus familiaris
715908 Macaca mulatta
100056571 Equus caballus
100151904 Sus scrofa
100358960 Oryctolagus cuniculus
100472270 Ailuropoda melanoleuca
100019951 Monodelphis domestica
100597840 Nomascus leucogenys
200186 Homo sapiens
74343 Mus musculus
310615 Rattus norvegicus
540959 Bos taurus
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