anti-Schwein CAMKK2 Antikörper für Western Blotting

Recommended CAMKK2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) Antikörper
  • camk2b
  • fj90d04
  • wu:fj90d04
  • si:dkey-174n20.2
  • CAMKK2
  • AI846603
  • CaMKKalpha
  • Camkk
  • CAMKK
  • CAMKKB
  • 6330570N16Rik
  • AW061083
  • mKIAA0787
  • calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
  • calcium/calmodulin dependent protein kinase kinase 2
  • calcium/calmodulin dependent protein kinase II beta
  • calcium/calmodulin-dependent protein kinase kinase 2, beta
  • calcium/calmodulin-dependent protein kinase kinase 1, alpha
  • calcium/calmodulin-dependent protein kinase kinase 2
  • camk2b1
  • CAMKK2
  • CAMK2B
  • camkk2
  • Camkk1
  • Camkk2
Epitop
N-Term
31
14
7
7
6
5
5
5
4
3
3
2
2
2
2
2
2
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Zebrafisch
92
56
31
2
1
1
1
1
1
1
1
Wirt
Kaninchen
96
14
Klonalität
Polyklonal
Konjugat
Dieser CAMKK2 Antikörper ist unkonjugiert
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
90
45
28
19
13
8
5
5
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2774040
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2617870 ICC IHC (p) WB Rabbit IgG AA 180-194 Anmelden zum Anzeigen Polyclonal

General

Antigen Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) Antikörper
Epitop N-Term
(31), (14), (7), (7), (6), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Zebrafisch
(92), (56), (31), (2), (1), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(96), (14)
Klonalität
Polyklonal
Konjugat Dieser CAMKK2 Antikörper ist unkonjugiert
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(90), (45), (28), (19), (13), (8), (5), (5), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CAMKK2 Antikörper

Target Details CAMKK2 Anwendungsinformationen Handhabung Referenzen für anti-CAMKK2 Antikörper (ABIN2774040) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN974428.
Sequenz GGLAAGGSLD MNGRCICPSL PYSPVSSPQS SPRLPRRPTV ESHHVSITGM
Homologie Cow: 93%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%, Zebrafish: 79%
Produktmerkmale This is a rabbit polyclonal antibody against CAMKK2. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CAMKK2

Target Details CAMKK2

Produktdetails anti-CAMKK2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CAMKK2 Antikörper (ABIN2774040) Bilder zurück nach oben
Antigen
Andere Bezeichnung CAMKK2 (CAMKK2 Antibody Abstract)
Hintergrund CAMKK2 is a calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 seems to be involved in hippocampal activation of CREB1.The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases.
Alias Symbols: CAMKK, CAMKKB, KIAA0787, MGC15254
Protein Interaction Partner: HSP90AA1, APP, UBC, NEDD4, CEP63, ESYT2, FANCI, OBSL1, ATG4B, XPOT, GCN1L1, IQGAP2, SMC3, SLC25A11, SMC1A, PRKDC, PRKAG1, PRKAA2, IRAK1, FLNC, FLNA, MAPK14, CALM1, CAMK4, CAMK1, PRKACA, SGK1,
Protein Size: 498
Molekulargewicht 55 kDa
Gen-ID 10645
NCBI Accession NM_153500, NP_705720
UniProt Q96RR4
Pathways AMPK Signaling

Anwendungsinformationen

Produktdetails anti-CAMKK2 Antikörper Target Details CAMKK2 Handhabung Referenzen für anti-CAMKK2 Antikörper (ABIN2774040) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 498 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CAMKK2 Antikörper Target Details CAMKK2 Anwendungsinformationen Referenzen für anti-CAMKK2 Antikörper (ABIN2774040) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CAMKK2 Antikörper (ABIN2774040)

Produktdetails anti-CAMKK2 Antikörper Target Details CAMKK2 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Erhardt, Lucae, Unschuld, Ising, Kern, Salyakina, Lieb, Uhr, Binder, Keck, Müller-Myhsok, Holsboer: "Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders." in: Journal of affective disorders, Vol. 101, Issue 1-3, pp. 159-68, 2007

Bilder

Produktdetails anti-CAMKK2 Antikörper Target Details CAMKK2 Anwendungsinformationen Handhabung Referenzen für anti-CAMKK2 Antikörper (ABIN2774040) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (N-Term) antibody (ABIN2774040) WB Suggested Anti-CAMKK2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (N-Term) antibody (ABIN2774040) Host: Rabbit
Target Name: CAMKK2
Sample Tissue: Human Fetal Liver
Western Blotting (WB) image for anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (N-Term) antibody (ABIN2774040) Host: Rabbit
Target Name: CAMKK2
Sample Tissue: Human Adult Placenta