NLRC4 (NLRC4) ELISA Kits

Bezeichnung:
NLR Family, CARD Domain Containing 4 ELISA Kits (NLRC4)
Auf www.antikoerper-online.de finden Sie aktuell 13 NLR Family, CARD Domain Containing 4 (NLRC4) ELISA Kits von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NLRC4 Antikörper (95) und NLRC4 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 116 NLRC4 Produkte verfügbar.
Synonyme:
9530011P19Rik, Card12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, IPAF
list all ELISA KIts Gen GeneID UniProt
NLRC4 58484 Q9NPP4
NLRC4 268973  
NLRC4 298784  

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Weitere ELISA Kits für NLRC4 Interaktionspartner

Human NLR Family, CARD Domain Containing 4 (NLRC4) Interaktionspartner

  1. Results found that NLRC4 expression increased in for promoting DN progression and demonstrate NLRC4-driven IL-1beta (zeige IL1B ELISA Kits) production as critical for the progression of DN.

  2. Ubiquitin-tagged NLRC4 could induce cell death and activate caspase-8 (zeige CASP8 ELISA Kits) independent of Ser (zeige SIGLEC1 ELISA Kits)(533) phosphorylation. Our

  3. LPS (zeige IRF6 ELISA Kits) activates the MAPK (zeige MAPK1 ELISA Kits) pathway in macrophages, thus resulting in the upregulation of NLRC4; however, NLRC4 inhibits IL1beta (zeige IL1B ELISA Kits) and IL18 (zeige IL18 ELISA Kits) production, contributing to the anti-inflammatory response.

  4. High expression of NLRP3 (zeige NLRP3 ELISA Kits), NLRC4, and CASP1 (zeige CASP1 ELISA Kits) in background non-tumorous liver is significantly correlated with poor prognosis of patients after resection of hepatocellular carcinoma.

  5. association of IL-18 (zeige IL18 ELISA Kits) levels with a single nucleotide polymorphism in the untranslated exon 2 of the inflammasome component NLRC4

  6. While both contributing to pathogen clearance, NLRP3 (zeige NLRP3 ELISA Kits) more than NLRC4 contributes to deleterious inflammatory responses in cystic fibrosis (zeige S100A8 ELISA Kits) and correlates with defective NLRC4-dependent IL-1Ra (zeige IL1RN ELISA Kits) production.

  7. analysis of a subset of inflammasome receptors including NLRP3 (zeige NLRP3 ELISA Kits), NLRC4 and AIM2 (zeige AIM2 ELISA Kits) that triggers formation of the micrometer-sized spherical supramolecular complex called the ASC (zeige PYCARD ELISA Kits) speck

  8. Thus, pathogenic inflammasome activity during Candida infection is negatively regulated by the IL-22 (zeige IL22 ELISA Kits)/NLRC4/IL-1Ra (zeige IL1RN ELISA Kits) axis.

  9. cN-II (zeige NT5C2 ELISA Kits) co-immunoprecipitated both with wild type Ipaf and its LRR domain after transfection with corresponding expression vectors, but not with Ipaf lacking the LRR domain.

  10. Elevated expression of IPAF was associated with inflammation in patients with pemphigus vulgaris (zeige DSG3 ELISA Kits) disease.

Mouse (Murine) NLR Family, CARD Domain Containing 4 (NLRC4) Interaktionspartner

  1. NLRC4 expression controls melanoma tumor growth.

  2. The interplay between NLRP3 (zeige NLRP3 ELISA Kits) and NLRC4 reveals an unexpected overlap between what had been considered distinct inflammasome scaffolds.

  3. The activation of NLRC4 by flagellin (zeige FliC ELISA Kits) downregulated the flagellin (zeige FliC ELISA Kits)-induced and TLR5 (zeige TLR5 ELISA Kits)-mediated immune responses against flagellin (zeige FliC ELISA Kits).

  4. TLR5 (zeige TLR5 ELISA Kits) but not NLRC4 is required for S. pneumoniae FliC (zeige FliC ELISA Kits)-induced protection.

  5. Data indicate that NLRC4 activation in Intestinal epithelial cells (IECs) leads to cell expulsion and IL-18 (zeige IL18 ELISA Kits) release, and implicate Caspase-8 (zeige CASP8 ELISA Kits) in NLRC4 inflammasome responses in vivo by generation of doubly deficient in Caspase-1 (zeige CASP1 ELISA Kits) and Caspase-8 (zeige CASP8 ELISA Kits).

  6. The tick protein sialostatin L2 binds to annexin A2 (zeige ANXA2 ELISA Kits) and inhibits NLRC4-mediated inflammasome activation.

  7. LPS (zeige TLR4 ELISA Kits) activates the MAPK (zeige MAPK1 ELISA Kits) pathway in macrophages, thus resulting in the upregulation of NLRC4; however, NLRC4 inhibits IL1beta (zeige IL1B ELISA Kits) and IL18 (zeige IL18 ELISA Kits) production, contributing to the anti-inflammatory response.

  8. These data reveal mild constitutive activation of the Nlrc4 inflammasome as the results of two SNPs, which leads to the stimulation of hepatocyte proliferation. The increased liver regeneration induces rapid liver mass recovery after hepatectomy and may prevent the development of hepatotoxin-induced liver fibrosis.

  9. While both contributing to pathogen clearance, NLRP3 (zeige NLRP3 ELISA Kits) more than NLRC4 contributes to deleterious inflammatory responses in cystic fibrosis (zeige S100A8 ELISA Kits) and correlates with defective NLRC4-dependent IL-1Ra (zeige IL1RN ELISA Kits) production.

  10. The wheel-like structure of a PrgJ-NAIP2-NLRC4 complex determined by cryogenic electronmicroscopy at 6.6 angstrom reveals that NLRC4 activation involves substantial structural reorganization that creates one oligomerization surface (catalytic surface).

NLRC4 Antigen-Profil

Beschreibung des Gens

In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.

Alternative names and synonyms associated with NLRC4

  • NLR family, CARD domain containing 4 (NLRC4) Elisa Kit
  • NLR family, CARD domain containing 4 (Nlrc4) Elisa Kit
  • 9530011P19Rik Elisa Kit
  • Card12 Elisa Kit
  • CLAN Elisa Kit
  • CLAN1 Elisa Kit
  • CLANA Elisa Kit
  • CLANB Elisa Kit
  • CLANC Elisa Kit
  • CLAND Elisa Kit
  • CLR2.1 Elisa Kit
  • IPAF Elisa Kit

Bezeichner auf Proteinebene für NLRC4

caspase recruitment domain protein 12 , NLR family CARD domain-containing protein 4 , ice protease-activating factor , ipaf , NLR family, CARD domain containing 4 , CARD, LRR, and NACHT-containing protein , ICE-protease activating factor , NOD-like receptor C4 , caspase recruitment domain family, member 12 , caspase recruitment domain-containing protein 12 , nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4

GENE ID SPEZIES
459135 Pan troglodytes
512480 Bos taurus
706378 Macaca mulatta
100070605 Equus caballus
58484 Homo sapiens
268973 Mus musculus
298784 Rattus norvegicus
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