anti-Mykobakterien Heat Shock Protein 65 Antikörper für Enzyme Immunoassay

Recommended Heat Shock Protein 65 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Heat Shock Protein 65 (HSP65) Antikörper
  • CPN60
  • GROEL
  • HLD4
  • HSP-60
  • HSP60
  • HSP65
  • HuCHA60
  • SPG13
  • heat shock 60kDa protein 1 (chaperonin)
  • HSPD1
Reaktivität
Mykobakterien
1
1
Wirt
Maus
2
Klonalität
Monoklonal
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
1
1
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN2859572
$ 866.25
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2859571 EIA WB Mouse IgG2a Anmelden zum Anzeigen BDI577

General

Antigen Heat Shock Protein 65 (HSP65) Antikörper
Reaktivität Mykobakterien
(1), (1)
Wirt Maus
(2)
Klonalität (Klon)
Monoklonal   ( )
Applikation Enzyme Immunoassay (EIA), Western Blotting (WB)
(1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Spezifität This antibody is reactive with Hsp65 (GroEL) of M. tuberculosis. Does not react with M. bovis, M. avium, M. phlei, M. parafortuitum, Rhodococcus sp., B. subtilis, S. pneumoniae, and E. coli.
Produktmerkmale Synonyms: 60 kDa chaperonin 2, Protein Cpn60-2, groEL protein 2, Cell wall protein A, Antigen A,groL2, groEL-2, groEL2, hsp65, Rv0440, MT0456, MTV037.04
Reinigung Protein A chromatography
Reinheit > 90 % pure
Immunogen Purified protein derivative (PPD)
Klon BDI578
Isotyp IgG2a

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Heat Shock Protein 65 / HSP65 (HSP65 Antibody Abstract)
Hintergrund Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure, most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.Synonyms: 60 kDa chaperonin 2, Antigen A, Cell wall protein A, MT0456, MTV037.04, Protein Cpn60-2, Rv0440, groEL protein 2, groEL-2, groEL2, groL2, hsp65
Gen-ID 886354
UniProt P0A520
Pathways Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikationshinweise ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Konzentration 0,1 mg/mL (OD280nm, E0.1% = 1.4)
Buffer 0.01 M PBS, pH 7.2 containing 0.09 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Haltbarkeit 12 months