Hemopoietic Cell Kinase ELISA Kits (HCK)
Auf www.antikoerper-online.de finden Sie aktuell 8 Hemopoietic Cell Kinase (HCK) ELISA Kits von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen HCK Antikörper (146) und HCK Proteine (16) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 183 HCK Produkte verfügbar.
AI849071, Bmk, HCK, Hctk, JTK9, laloo, MGC107870, p56Hck, p59Hck, p61Hck

Weitere ELISA Kits für HCK Interaktionspartner

Human Hemopoietic Cell Kinase (HCK) Interaktionspartner

  1. Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck-dependent activation of PKCdelta (zeige PKCd ELISA Kits), which stimulates PKCgamma (zeige PRKCG ELISA Kits), resulting in translocation of phosphorylated p47(phox).

  2. HCK represents a novel target for therapeutic development in MYD88 (zeige MYD88 ELISA Kits)-mutated Waldenstrom macroglobulinemia and activated-B cell diffuse large B-cell lymphoma, and possibly other diseases driven by mutated MYD88 (zeige MYD88 ELISA Kits).

  3. High HCK levels correlate with reduced survival of colorectal cancer patients and is associated with activated macrophages gene signature.

  4. three-dimensional (3D) QSAR pharmacophore models were generated for Hck based on experimentally known inhibitors. A best pharmacophore model, Hypo1, was developed with high correlation coefficient (0.975), Low RMS deviation (0.60) and large cost difference (49.31), containing three ring aromatic and one hydrophobic aliphatic feature

  5. we provide evidence for involvement of HCK and FGR (zeige FGR ELISA Kits) in FCRL4 (zeige FCRL4 ELISA Kits)-mediated immunoregulation and for the functional importance of posttranslational modifications of the FCRL4 (zeige FCRL4 ELISA Kits) molecule.

  6. Interaction with the Src (zeige SRC ELISA Kits) homology (SH3-SH2) region of the Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.

  7. Interaction between Nef and Hck is important for Nef-dependent modulation of viral infectivity.

  8. Data indicate that combined treatment using SFK (LYN (zeige LYN ELISA Kits), HCK, or FGR (zeige FGR ELISA Kits)) and c-KIT (zeige KIT ELISA Kits) inhibitor dasatinib dasatinib and chemotherapy provides a novel approach to increasing p53 (zeige TP53 ELISA Kits) activity and enhancing targeting of acute myeloid leukemia (zeige BCL11A ELISA Kits) (AML (zeige RUNX1 ELISA Kits)) stem cells.

  9. The SRC (zeige SRC ELISA Kits) family tyrosine kinase (zeige TXK ELISA Kits) HCK and the ETS (zeige ETS1 ELISA Kits) family transcription factors SPIB (zeige SPIB ELISA Kits) and EHF (zeige EHF ELISA Kits) regulate transcytosis across a human follicle-associated epithelium model.

  10. This particular binding mode enables Hck SH3 to sense a specific non-canonical residue situated in the SH3 RT-loop of the kinase.

Mouse (Murine) Hemopoietic Cell Kinase (HCK) Interaktionspartner

  1. the Hck, Fgr (zeige FGR ELISA Kits) and Lyn (zeige LYN ELISA Kits) kinases are also necessary for amastigote uptake by macrophages. Src (zeige SRC ELISA Kits)-mediated Arg activation is required for efficient uptake.

  2. Hematopoietic Hck promotes tumorigenesis.

  3. Data suggest that Hck is a key mediator of renal fibrosis

  4. Data indicate that Src (zeige SRC ELISA Kits)-Family Kinases Hck and Fgr (zeige FGR ELISA Kits) regulate cytokine secretion by macrophages.

  5. Hck is not only progressively overexpressed in atherosclerosis, but it also controls critical molecular processes in monocyte influx, blood monocyte subset balance, macrophage accumulation, and the maintenance of atherosclerotic lesion stability.

  6. The Src (zeige SRC ELISA Kits) family kinases Hck, Fgr (zeige FGR ELISA Kits), and Lyn (zeige LYN ELISA Kits) are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.

  7. tyrosine phosphorylation of WASP (zeige WASL ELISA Kits) by Hck is required for proper macrophage functions

  8. Hck is one of the very few effectors of preosteoclast recruitment described to date and thereby plays a critical role in bone remodeling.

  9. Despite possessing enhanced killing, alveolar macrophage Hck/Fgr (zeige FGR ELISA Kits)/Lyn (zeige LYN ELISA Kits)-deficient ("triple-knockout") mice do not demonstrate enhanced inflammatory responses to Pneumocystis murina.

  10. Taken together, PKR (zeige EIF2AK2 ELISA Kits) and Hck were critical for DON-induced ribosomal recruitment of p38 (zeige CRK ELISA Kits), its subsequent phosphorylation, and, ultimately, p38 (zeige CRK ELISA Kits)-driven proinflammatory cytokine expression.

Cow (Bovine) Hemopoietic Cell Kinase (HCK) Interaktionspartner

  1. A truncated, mRNA-encoded src-related tyrosine kinase (zeige FRK ELISA Kits) HCK could function as an adaptor protein or as a competitive inhibitor in spermiogenesis or mature sperm functions.

  2. the presence of mRNAs encoding for hck and hck-tr in testicular germ cells; hck-tr being translated during spermatogenesis and expressed on mature ejaculated bull spermatozoa.

HCK Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Alternative names and synonyms associated with HCK

  • hemopoietic cell kinase (tklal-a) Elisa Kit
  • hemopoietic cell kinase (HCK) Elisa Kit
  • hemopoietic cell kinase (hck) Elisa Kit
  • hemopoietic cell kinase (Hck) Elisa Kit
  • AI849071 Elisa Kit
  • Bmk Elisa Kit
  • HCK Elisa Kit
  • Hctk Elisa Kit
  • JTK9 Elisa Kit
  • laloo Elisa Kit
  • MGC107870 Elisa Kit
  • p56Hck Elisa Kit
  • p59Hck Elisa Kit
  • p61Hck Elisa Kit

Bezeichner auf Proteinebene für HCK

hemopoietic cell kinase , non-receptor protein tyrosine kinase laloo , tyrosine-protein kinase HCK-like , hematopoietic cell kinase , p59-HCK/p60-HCK , tyrosine-protein kinase HCK , B cell/myeloid kinase , B-cell/myeloid kinase , p56-HCK/p59-HCK , hemopoietic cell tyrosine kinase , p56-HCK

373700 Xenopus laevis
458163 Pan troglodytes
485828 Canis lupus familiaris
548439 Xenopus (Silurana) tropicalis
100455620 Pongo abelii
100587780 Nomascus leucogenys
3055 Homo sapiens
15162 Mus musculus
25734 Rattus norvegicus
419280 Gallus gallus
280814 Bos taurus
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