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Rat (Rattus) BDKRB2 ELISA Kit für Sandwich ELISA - ABIN432735
Siltari, Korpela, Vapaatalo: Bradykinin -induced vasodilatation: Role of age, ACE1-inhibitory peptide, mas- and bradykinin receptors. in Peptides 2016
The most characteristic signaling pathways for B2R and D2R (zeige DRD2 ELISA Kits), dependent on intracellular Ca(2 (zeige CA2 ELISA Kits)+) and cAMP concentration, respectively, were analyzed in cells presenting similar endogenous expression of B2R and D2R.The evidence of B2R-D2R (zeige DRD2 ELISA Kits) dimerization may open new perspectives in the modulation of diverse cellular functions which depend on their activation.
These results indicate that KOR (zeige OPRK1 ELISA Kits) can form a heterodimer with B2R and this leads to increased protein kinase A activity by the CREB (zeige CREB1 ELISA Kits) signaling pathway, leading to a significant increase in cell proliferation.
Study demonstrated the ability of long-chain polyunsaturated fatty acids to act as agonist to the B2R at nanomolar concentrations and to induce receptor conformational changes.
Data suggest that N-myc (and STAT) interactor (NMI (zeige NMI ELISA Kits)) could improve its downstream target bradykinin B2 receptor (BDKRB2) expression to induce extracellular signal-regulated kinases (ERK) 1 (zeige MAPK3 ELISA Kits)/2 activation, and thereby further evoke malignant progression of hepatocellular carcinoma (HCC (zeige FAM126A ELISA Kits)).
Data show that mRNA and protein of bradykinin type 2 receptors, but not bradykinin type 1 receptors, were abundant in cultured c-Kit (zeige KIT ELISA Kits)+ progenitor cells.
BDKRB2 +9/-9 bp polymorphisms affected the gene expression and nitric oxide production, which were associated with radiographic severity of osteoarthritis, suggesting that the BDKRB2 +9/ -9 bp polymorphisms may act as a genetic modulator of osteoarthritis, and play an essential role in inflammatory process in osteoarthritis.
authors found significant interactions among PRKCA (zeige PKCa ELISA Kits), NOS3 and BDKRB2 genotypes associated with enalapril responses.
Bronchial B2R expression is constitutively elevated in allergic asthma and is further increased after allergen exposure together with NF-kB expression.
Report the presence of nuclear B2R in the utero-placental unit and reduced abundance of nuclear B2R in extravillous trophoblast in preeclampsia.
Data provide evidence that the BDKRB2 +9/-9 polymorphisms influence pro-inflammatory cytokine levels in knee osteoarthritis by altering TLR-2 (zeige TLR2 ELISA Kits) expression.
B2R signaling promotes aortic rupture within a ApoE (zeige APOE ELISA Kits)-eficient mouse model associated with the ability to stimulate inflammatory phenotypes of neutrophils and vascular smooth muscle cells.
B2R activation occurs in the diabetic skin and delays wound healing. B2R blockade improves skin wound healing in diabetic mice and is a potential therapeutic approach to diabetic ulcers.
a novel pathway by which C5aR (zeige C5AR1 ELISA Kits)/B2R cross-talk couples transendothelial leakage of plasma proteins to the cytokine circuitry that coordinates antiparasite immunity.
investigated if expression of B1 and B2 kinin receptors can be affected by IL-4 (zeige IL4 ELISA Kits) and IL-13 (zeige IL13 ELISA Kits); data show, for the first time, that IL-4 (zeige IL4 ELISA Kits) and IL-13 (zeige IL13 ELISA Kits) decrease kinin receptors in a STAT6 (zeige STAT6 ELISA Kits)-dependent mechanism
Data suggest that nicotine impairs mucosa-dependent Bdkrb2 (bradykinin B2 receptor) mediated trachea relaxation; nicotine also down-regulates tracheal expression of COX2/Ptgs2 (cyclooxygenase 2 (zeige PTGS2 ELISA Kits)) and mPGES-1 (zeige PTGES ELISA Kits) (microsomal prostaglandin E2 synthase-1).
Data suggest that expression of Bdkrb2 is up-regulated in adrenal medulla as the result of immobilization stress; data from CRH (corticotropin-releasing hormone (zeige CRH ELISA Kits)) knockout mice suggest this up-regulation requires catecholaminergic glucocorticoids.
B1R (zeige BDKRB1 ELISA Kits) and B2R receptors exert a critical role in the establishment of persistent hypersensitivity observed in an experimental autoimmune encephalomyelitis model
Data indicate that Bdkrb2(-/-) mice have elevated plasma angiotensin-(1-7) and messenger RNA and protein for its receptor Mas (zeige MAS1 ELISA Kits).
Null mutations at the p66 (zeige POLD3 ELISA Kits) and bradykinin 2 receptor loci induce divergent phenotypes in the diabetic kidney in mice.
These findings suggest that activation of the bradykinin/B2R pathway contributes to development of host resistance to visceral leishmaniasis.
A persistent B2R-beta2AR (zeige ADRB2 ELISA Kits) heterodimer was confirmed in bradykinin-stimulated and non-stimulated left ventricular myocardium. BK transactivation of beta2AR (zeige ADRB2 ELISA Kits) enhanced beta2AR (zeige ADRB2 ELISA Kits)-mediated release of tPA (zeige PLAT ELISA Kits).
This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.
B2 bradykinin receptor
, BK-2 receptor
, bradykinin B2 receptor
, ornithokinin receptor
, bradykinin receptor B2
, B2 bradykinin receptor-like
, b2 bradykinin receptor-like
, bradykinin receptor, beta 2
, kinin B2