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Applikationshinweise
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An antineoplastic antibiotic. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells. A potent inducer of apoptosis in many cell lines (1).
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Reinheit
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>98% by TLC
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Buffer
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Solubility: Soluble in DMSO (20 mg/ml)
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Lagerung
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Store powder at -20 o C for up to one year. Store solutions at -20 o C for up to 3 months.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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