Actinomycin D (10 mM)

Applikation: Funktionale Studien (Func), Enzymaktivitätsmessung (EAA)

Produktnummer: ABIN412354

Produktbeschreibung

Produktmerkmale: Molecular formular: C 62 H 86 N 12 O 16

Beschreibung: An antineoplastic antibiotic. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells. A potent inducer of apoptosis in many cell lines (1).

Molekulargewicht: 1255.5

Anwendungen

Applikationshinweise: We recommend using 1000X dilutions for inducing apoptosis in Jurkat cells (e.g., Add 1 μ l to 1 ml of culture medium). However, the optimal doses may vary for different cells and culture conditions.

Reinheit: >98% by HPLC

Lagerung: Store at -20 o C. SHELF LIFE: Stable for up to 3 months at -20 o C .

Beschränkungen: Nur für Forschungszwecke einsetzbar