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SERPINB9 encodes a member of the serine protease inhibitor family which are also known as serpins. Zusätzlich bieten wir Ihnen SERPINB9 Proteine (8) und SERPINB9 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal SERPINB9 Primary Antibody für FACS - ABIN2476137
Hall, Keane: Proceedings: Dopaminergic and cholinergic interactions in the caudate nucleus in relation to the induction of sleep in the cat. in British journal of pharmacology 1975
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Human Monoclonal SERPINB9 Primary Antibody für IHC (fro), FACS - ABIN2476136
Hirst, Buzza, Sutton, Trapani, Loveland, Bird: Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction. in Molecular human reproduction 2001
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Mouse (Murine) Polyclonal SERPINB9 Primary Antibody für FACS, WB - ABIN2192172
Zhang, Byrne, Liu, Wang, Oxenius, Ashton-Rickardt: Differential survival of cytotoxic T cells and memory cell precursors. in Journal of immunology (Baltimore, Md. : 1950) 2007
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Human Polyclonal SERPINB9 Primary Antibody für ELISA, WB - ABIN188847
Jiang, Ellison, Alarid, Shapiro: Interplay between the levels of estrogen and estrogen receptor controls the level of the granzyme inhibitor, proteinase inhibitor 9 and susceptibility to immune surveillance by natural killer cells. in Oncogene 2007
Data suggest that reactive oxygen species (ROS (zeige ROS1 Antikörper)) generated within cytotoxic lymphocytes by receptor stimulation are required for lysosomal permeabilization and release of GzmB (granzyme B (zeige Gzmb Antikörper)) into the cytosol and for inactivation of serpin B9.
the negative regulation of DC priming of CD8 (zeige CD8A Antikörper) T lymphocyte immunity by CTL killing is mitigated by the physiological inhibition of GrB by Spi6.
SPI-CI (zeige OVA Antikörper) is a novel immune escape molecule that acts in concert with SPI (zeige CHGA Antikörper)-6 to prevent cytotoxic lymphocyte-mediated killing of tumor cells.
Estrogen induction of PI-9 may reduce the ability of cytolytic lymphocytes-mediated immune surveillance to destroy newly transformed cells
In mCAP3 (zeige ST14 Antikörper), an intact catalytic triad was necessary for activation of ENaC (zeige SCNN1A Antikörper) but not for intramolecular cleavage of the protease.
protects hepatocytes against excessively vigorous granzyme B (zeige Gzmb Antikörper)-dependent killing but may also delay immune clearance of virally infected hepatocytes
deficiency in a weak intracellular inhibitor of neutrophil elastase (zeige ELANE Antikörper) results in an acute inflammatory response that protects from P. aeruginosa but does not cause lung disease
SPI (zeige CHGA Antikörper)-6 is selectively up-regulated in hepatocytes in response to infiltration of the liver by NK cells that express perforin (zeige PRF1 Antikörper) and enzymatically active granzyme B (zeige Gzmb Antikörper).
Increased SPI (zeige CHGA Antikörper)-6 expression is not sufficient to confer lipopolysaccharide-treated dendritic cells with resistance to direct killing in vivo.
Data show that the serine protease inhibitor B9 (serpinB9) mediated caspase-1 (zeige CASP1 Antikörper) inhibition regulates IL-1beta (zeige IL1B Antikörper) release in monocytes.
Treatment with estrogens further increased PI-9 level while decreased that of ERalpha66 isoform thus excluding the involvement of this receptor isoform in the event. Moreover, our studies also provided evidence that tertiary tumorspheres express elevated levels of CXCR4 (zeige CXCR4 Antikörper) and phospho-p38 (zeige CRK Antikörper), suggesting that the high PI-9 content might be ascribed to the activation of the proliferative CXCR4 (zeige CXCR4 Antikörper)/phospho-p38 (zeige CRK Antikörper) axis.
We filtered four OSCC genes including SERPINB9, SERPINE2 (zeige SERPINE2 Antikörper), GAK (zeige GAK Antikörper), and HSP90B1 (zeige HSP90B1 Antikörper) through the gene global prioritization score (P < 0.005).
Data show that oropharyngeal squamous cell carcinomas (OPSCCs) express granzyme inhibitors SERPINB1 (zeige SERPINB1 Antikörper), SERPINB4 (zeige SERPINB4 Antikörper) and SERPINB9 for cytotoxicity and the expression was not different between human papillomavirus (HPV)-positive and HPV-negative tumors.
Pediatric CNS-PNETs evade immune recognition by downregulating cell surface MHC (zeige HLAE Antikörper)-I and CD1d (zeige CD1D Antikörper) expression. Intriguingly, expression of SERPINB9, SERPINB1 (zeige SERPINB1 Antikörper), and SERPINB4 (zeige SERPINB4 Antikörper) is acquired during tumorigenesis in 29%, 29%, and 57% of the tumors
Increased intracellular PI-9 activity in mononuclear phagocytes from HIV-infected patients contributes to successful intracellular infection by virulent Mycobacterium tuberculosis.
Suppression of granzyme B (zeige Gzmb Antikörper) initiated apoptosis in protease inhibitor-9-expressing leukemia cells.
SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3 (zeige TLR3 Antikörper), MDA5 (zeige IFIH1 Antikörper) and RIG-I (zeige DDX58 Antikörper) during subclinical rejection.
lung cancer cells utilise their increased PI-9 expression to protect from granzyme B (zeige Gzmb Antikörper)-mediated cytotoxicity as an immune evasion mechanism
This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6.
serine (or cysteine) peptidase inhibitor, clade B, member 9
, serpin B9
, serpin peptidase inhibitor, clade B (ovalbumin), member 9
, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9
, Cytoplasmic antiproteinase 3
, serpin B9-like
, serine (or cysteine) proteinase inhibitor, clade B, member 9
, serine protease inhibitor 6
, cytoplasmic antiproteinase 3
, peptidase inhibitor 9
, protease inhibitor 9 (ovalbumin type)
, serpin peptidase inhibitor, clade B, member 9