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anti-serine Hydroxymethyltransferase 2 (Mitochondrial) (SHMT2) Antikörper

SHMT2 encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. Zusätzlich bieten wir Ihnen SHMT2 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SHMT2 6472 P34897
SHMT2 108037  
SHMT2 299857  
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Top anti-SHMT2 Antikörper auf antikoerper-online.de

Showing 10 out of 33 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Huhn Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: SHMT2 Antibody [NBP1-80754] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) Western Blot: SHMT2 Antibody [NBP1-80754] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
418,75 €
Details
Human Kaninchen Unkonjugiert IHC, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
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Human Kaninchen Unkonjugiert IHC, WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Hund Kaninchen Unkonjugiert IHC, ELISA, WB 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
374,52 €
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Western blot analysis of extracts of various cell lines, using SHMT2 antibody. 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Details
Human Maus Unkonjugiert IHC, WB Immunohistochemistry: SHMT2 Antibody (3E9) [NBP2-45826] - Analysis of Carcinoma of Human thyroid tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120 for 3 min) Immunohistochemistry: SHMT2 Antibody (3E9) [NBP2-45826] - Analysis of Human lymph node tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min) 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
426,25 €
Details
Maus Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cell lines, using SHMT2 antibody. 100 μL Anmelden zum Anzeigen 7 bis 8 Tage
282,86 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: SHMT2 Antibody [NBP2-20354] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:500 dilution. Immunohistochemistry-Paraffin: SHMT2 Antibody [NBP2-20354] - Immunohistochemical analysis of paraffin-embedded HeLa xenograft, using antibody at 1:500 dilution. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
426,25 €
Details

SHMT2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human , ,
,
,
Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-SHMT2 Antikörper

  1. Chicken Polyclonal SHMT2 Primary Antibody für IHC, WB - ABIN2782503 : Fu, Rife, Schirch: The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in MCF-7 cells as determined by (13)C NMR. in Archives of biochemistry and biophysics 2001 (PubMed)

  2. Human Polyclonal SHMT2 Primary Antibody für ICC, IF - ABIN4353389 : Kim, Fiske, Birsoy, Freinkman, Kami, Possemato, Chudnovsky, Pacold, Chen, Cantor, Shelton, Gui, Kwon, Ramkissoon, Ligon, Kang, Snuderl, Vander Heiden, Sabatini: SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. in Nature 2015 (PubMed)

Weitere Antikörper gegen SHMT2 Interaktionspartner

Human serine Hydroxymethyltransferase 2 (Mitochondrial) (SHMT2) Interaktionspartner

  1. The SHMT-2 is the direct targets of miR (zeige MLXIP Antikörper)-370 and miR (zeige MLXIP Antikörper)-373, respectively, in human articular chondrocytes.

  2. High SHMT2 expression increases glycine-dependent nucleotide synthesis leading to bladder cancer growth.

  3. SHMT2 is required for glioblastoma multiforme cells to adapt to the tumour environment, but also renders these cells sensitive to glycine cleavage system inhibition

  4. SHMT1 (zeige SHMT1 Antikörper) exists in solution as a tetramer, both in the absence and presence of PLP (zeige PLP1 Antikörper), while SHMT2 undergoes a dimer-to-tetramer transition.

  5. The present study not only describes individual genetic variation that directly affects SHMT1 (zeige SHMT1 Antikörper) and SHMT2 activity, but provided insight into the overall regulation of the Folate and Methionine Cycles.

  6. SHMT1 (zeige SHMT1 Antikörper) and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis

Mouse (Murine) serine Hydroxymethyltransferase 2 (Mitochondrial) (SHMT2) Interaktionspartner

  1. SHMT1 (zeige SHMT1 Antikörper) and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis

SHMT2 Antigen-Profil

Protein Überblick

This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit SHMT2

  • serine hydroxymethyltransferase 2 (mitochondrial) (Chro.80302) Antikörper
  • serine hydroxymethyltransferase 2 (mitochondrial) (shmt2) Antikörper
  • serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2) Antikörper
  • serine hydroxymethyltransferase 2 (mitochondrial) (Shmt2) Antikörper
  • 2700043D08Rik Antikörper
  • AA408223 Antikörper
  • AA986903 Antikörper
  • GLYA Antikörper
  • SHMT Antikörper

Bezeichner auf Proteinebene für SHMT2

serine hydroxymethyltransferase 2 (mitochondrial) , mitochondrial serine hydroxymethyltransferase , serine hydroxymethyltransferase, mitochondrial , GLY A+ , glycine auxotroph A, human complement for hamster , glycine hydroxymethyltransferase , serine aldolase , serine hydroxymethylase , serine methylase , threonine aldolase , SHMT

GENE ID SPEZIES
3412258 Cryptosporidium hominis TU502
100144628 Danio rerio
447193 Xenopus laevis
6472 Homo sapiens
607458 Canis lupus familiaris
507197 Bos taurus
100009293 Oryctolagus cuniculus
108037 Mus musculus
299857 Rattus norvegicus
Ausgewählte Anbieter für anti-SHMT2 (SHMT2) Antikörper
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