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Members of the Rho GTPase family, such as RND1, regulate the organization of the actin cytoskeleton in response to extracellular growth factors (Nobes et al., 1998 [PubMed 9531558]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen RND1 Kits (9) und RND1 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.
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The authors propose that anillin (zeige ANLN Antikörper) is required for proper Rho-GTP (zeige AK3 Antikörper) distribution at cell-cell junctions and for maintenance of a robust apical actomyosin belt, which is required for cell-cell junction integrity.
Studies suggest that Rho GTPase (zeige RACGAP1 Antikörper) signalling is a complicated mechanism in RhoA (zeige RHOA Antikörper)-driven cancer cell invasive migration.
RND1 plays an important role in the progression of esophageal squamous cell carcinoma
These results reveal a previously unappreciated mechanism through which Rnd1 restrains activation of Ras-MAPK (zeige MAPK1 Antikörper) signalling and breast tumour initiation and progression
Data indicate that Rnd1 efficiently displaces Rac1 from its complex with Plexin-B1 (zeige PLXNB1 Antikörper) but not vice versa.
role of the N-terminal region in signaling; Rnd1 and Rnd3 (zeige RND3 Antikörper) have a KERRA (Lys (zeige LYZ Antikörper)-Glu (zeige DCTN1 Antikörper)-Arg-Arg-Ala) sequence of amino acids in their N-terminus, which functions as the lipid raft-targeting determinant; the sequence mediates lipid raft targeting of p190 RhoGAP (zeige GRLF1 Antikörper) correlated with its activation
Rnd1 does not play a role in the activation of plexin-C1 (zeige PLXNC1 Antikörper) and -D1
Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers
The RND1 mRNA expression levels increased significantly after gestation in myometria.
Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase (zeige RACGAP1 Antikörper) interaction motif destabilizes dimerization of the plexin-B1 (zeige PLXNB1 Antikörper) effector domain
SCG10 (zeige STMN2 Antikörper) acts as an effector downstream of Rnd1 to regulate axon extensions by modulating microtubule organization.
Members of the Rho GTPase family, such as RND1, regulate the organization of the actin cytoskeleton in response to extracellular growth factors (Nobes et al., 1998
Rho family GTPase 1
, GTP-binding protein
, ras-like protein Rnd1b
, rho-related GTP-binding protein Rho6
, ras homolog gene family, member S