anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) Antikörper

PEA15 encodes a death effector domain-containing protein, which is a major phosphoprotein in astrocytes, and an endogenous substrate for protein kinase C. Zusätzlich bieten wir Ihnen PEA15 Proteine (13) und PEA15 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PEA15 8682 Q15121
PEA15 364052 Q5U318
PEA15 18611 Q62048
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Showing 10 out of 111 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-PEA15 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-PEA15 Antibody <br /> Positive Control: Lane 1:241 µg EGFP-transfected MCF7 lysate Lane 2: 041 µg EGFP-PEA15 transfected MCF7 lysate <br />Primary Antibody Dilution: 1:0000<br />Secondary Antibody: Goat anti-rabbit-HRP Secondry <br /> Antibody Dilution: 1:0000<br />Submitted by: Yann Wallez (Sanford-Burnham Medical Research Institute) 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of PEA-15 Antibody (C-term) (ABIN652463) in T47D cell line lysates (35 µg/lane).PEA-15 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of PEA-15 Antibody (C-term) (ABIN652463) in mouse lung tissue lysates (35 µg/lane).PEA-15 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, WB (LEFT) Western blot analysis of PEA-15 Antibody (C-term) in T47D cell line lysates (35ug/lane).PEA-15 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of PEA-15 Antibody (C-term) in mouse lung tissue lysates (35ug/lane).PEA-15 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IF, ELISA Immunofluorescence analysis of MCF7 cells, using PEA15 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from COS7 cells treated with TNF 20ng/ml 5', using PEA-15 (Phospho-Ser104) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart, using PEA-15 (Phospho-Ser104) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-PEA15 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human brain WB Suggested Anti-PEA15 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Human brain 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
385,00 €
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from COS7 cells treated with INSULIN 0.01U/ML 15', using PEA-15 (Phospho-Ser116) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using PEA-15 (Phospho-Ser116) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western Blot (WB) analysis of COLO205 3T3 using p-PEA-15 (S116) antibody. 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
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PEA15 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PEA15 Antikörper

  1. Human Polyclonal PEA15 Primary Antibody für FACS, IHC (p) - ABIN652463 : Trencia, Perfetti, Cassese, Vigliotta, Miele, Oriente, Santopietro, Giacco, Condorelli, Formisano, Beguinot: Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action. in Molecular and cellular biology 2003 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen PEA15 Interaktionspartner

Human phosphoprotein Enriched in Astrocytes 15 (PEA15) Interaktionspartner

  1. PEA15 expression was not significantly correlated with ovarian cancer antineoplastic drug resistance.

  2. Data suggest the role of the phospholipase C epsilon (zeige PLCL1 Antikörper)-Protein kinase D (zeige PRKD1 Antikörper)-PEA15 protein-ribosomal S6 kinase (zeige RPS6KB1 Antikörper)-IkappaB-NF-kappa B (zeige NFKB1 Antikörper) pathway in facilitating inflammation and inflammation-associated carcinogenesis in the colon.

  3. Integrin alpha5beta1 and p53 (zeige TP53 Antikörper) convergent pathways in the control of anti-apoptotic proteins PEA-15 and survivin (zeige BIRC5 Antikörper) in high-grade glioma.

  4. High PED expression is associated with esophageal carcinoma.

  5. The nuclear translocation of SApErk1/ 2 apart from PEA-15 as an important mechanism to reverse senescence phenotype.

  6. Latent HCMV infection of CD34 (zeige CD34 Antikörper) + cells protects cells from FAS (zeige FAS Antikörper)-mediated apoptosis through the cellular IL-10 (zeige IL10 Antikörper)/PEA-15 pathway.

  7. New therapeutic targets based around PEA-15 and its associated interactions are now being uncovered and could provide novel avenues for treatment strategies in multiple diseases.

  8. PED/PEA-15 overexpression is sufficient to block hydrogen peroxide-induced apoptosis in Ins-1E cells through a PLD-1 mediated mechanism

  9. Omi/HtrA2 (zeige HTRA2 Antikörper) overexpression promotes hepatocellular carcinoma cell apoptosis and the ped/pea-15 expression level causes this difference of the Omi/HtrA2 (zeige HTRA2 Antikörper) pro-apoptotic marker in the various hepatocellular carcinoma cell lines

  10. Results suggest that neurochemical adaptations of brain FADD (zeige FADD Antikörper), as well as its interaction with PEA-15, could play a major role to counteract the known activation of the mitochondrial apoptotic pathway in major depression

Mouse (Murine) phosphoprotein Enriched in Astrocytes 15 (PEA15) Interaktionspartner

  1. Data suggest that PEA-15 contributes to the specification of the cytokine pattern of activated Th cells, thus highlighting a potential new target to interfere with T cell functional polarization and subsequent immune response.

  2. PED/PEA-15 overexpression is sufficient to block hydrogen peroxide-induced apoptosis in Ins-1E cells through a PLD-1 mediated mechanism

  3. Activated astrocytes are known to clear the Abeta (zeige APP Antikörper) deposited in the extracellular milieu, which is why they play a key role in regulating the progression of Alzheimer's disease (AD).

  4. Activation of peroxisome proliferator-activated receptor-gamma (PPARgamma (zeige PPARG Antikörper)) represses transcription of the ped/pea-15 gene.

  5. The findings revealed a novel mechanism by which PEA-15 positively regulates Ras/ERK signaling and increases the proliferation of H-Ras-transformed epithelial cells through enhanced phospholipase D1 expression and activation.

  6. PEA-15 did not differentiate and showed markedly enhanced autophagy. In these same cells, the autophagy inhibitor 3 (zeige PPP1R11 Antikörper)-methyladenine rescued TGF-beta1 (zeige TGFB1 Antikörper) effect on both autophagy and myogenesis, indicating that PEA-15 mediates TGF-beta1 (zeige TGFB1 Antikörper) effects in muscle.

  7. Data suggest that PED/PEA-15 may affect fibroblast motility by a mechanism, at least in part, mediated by ERK1/2 (zeige MAPK1/3 Antikörper).

  8. we propose that PEA-15 represents a novel point of convergence of the protein kinas C and MAPK/ERK (zeige MAPK1 Antikörper) pathways under gonadotropin releasing hormone stimulation

  9. PEA-15 regulates T-cell proliferation

  10. PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase.

PEA15 Antigen-Profil

Protein Überblick

This gene encodes a death effector domain-containing protein, which is a major phosphoprotein in astrocytes, and an endogenous substrate for protein kinase C. Studies using knockout mice suggest that this protein may protect astrocytes from TNF-induced apoptosis. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake.

Genbezeichner und Symbole assoziert mit PEA15

  • phosphoprotein enriched in astrocytes 15 (PEA15) Antikörper
  • phosphoprotein enriched in astrocytes 15 (pea15) Antikörper
  • Astrocytic phosphoprotein PEA-15 (pea15) Antikörper
  • phosphoprotein enriched in astrocytes 15 (Pea15) Antikörper
  • phosphoprotein enriched in astrocytes 15A (Pea15a) Antikörper
  • DKFZp459O1410 Antikörper
  • HMAT1 Antikörper
  • HUMMAT1H Antikörper
  • Mat1 Antikörper
  • MAT1H Antikörper
  • PEA-15 Antikörper
  • Pea15 Antikörper
  • Pea15a Antikörper
  • PED Antikörper
  • Pkcs15 Antikörper

Bezeichner auf Proteinebene für PEA15

phosphoprotein enriched in astrocytes 15 , Astrocytic phosphoprotein PEA-15 , 15 kDa phosphoprotein enriched in astrocytes , Phosphoprotein enriched in astrocytes, 15kD , astrocytic phosphoprotein PEA-15 , homolog of mouse MAT-1 oncogene , phosphoprotein enriched in diabetes , phosphoprotein enriched in astrocytes 15A , mammary transforming gene 1

GENE ID SPEZIES
677706 Macaca mulatta
705026 Macaca mulatta
100145359 Xenopus (Silurana) tropicalis
100152480 Sus scrofa
100174153 Pongo abelii
100286636 Salmo salar
8682 Homo sapiens
364052 Rattus norvegicus
734852 Xenopus laevis
510586 Bos taurus
610113 Canis lupus familiaris
18611 Mus musculus
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