anti-anthrax Toxin Receptor 1 (ANTXR1) Antikörper

ANTXR1 encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. Zusätzlich bieten wir Ihnen anthrax Toxin Receptor 1 Proteine (14) und anthrax Toxin Receptor 1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ANTXR1 84168 Q9H6X2
ANTXR1 69538 Q9CZ52
ANTXR1 362393 Q0PMD2
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Showing 10 out of 177 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-ANTXR1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert DB Dot blot analysis of anti-Phospho-ANTXR1-pY382 Antibody (ABIN389930) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert DB Dot blot analysis of anti-Phospho-ANTXR1-pY425 Antibody (ABIN389986) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-ANTXR1 Antibody (Y382)(ABIN392154) in Hela cell line lysates (35 µg/lane). ANTXR1 (arrow) was detected using the purified polyclonal antibody (1:60dilution). Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ANTXR1 Antibody (Y382) (ABIN392154), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185280 staining (0.3 ug/ml) of Human PBMC lysate (RIPA buffer, 35 ug total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
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Human Kaninchen Unkonjugiert WB Western blot analysis of TEM8 using lysates from rat kidney  (Lane 1), mouse small intestine (Lane 2), and Jurkat cells (Lane 3). 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
Details
Human Maus Unkonjugiert ICC, IF, IHC (p), IHC, WB Western blot detection of TEM8 in TEM8 transfected cell lysate using ABIN252540 at 1 ug/ml. Immunohistochemistry-Paraffin: TEM8/ANTXR1 Antibody (200C1339(SB20)) [ABIN2525395] - Formalin-fixed paraffin-embedded section of human colon stained with TEM8 antibody at 2.5 ug/ml concentration using DAB chromogen detection method (10X magnification) 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details

ANTXR1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-anthrax Toxin Receptor 1 Antikörper

  1. Human Monoclonal ANTXR1 Primary Antibody für ICC, IF - ABIN252539 : Matsuda, Ohga, Hida, Muraki, Tsuchiya, Kurosu, Akino, Shih, Totsuka, Klagsbrun, Shindoh, Hida: Isolated tumor endothelial cells maintain specific character during long-term culture. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal ANTXR1 Primary Antibody für ELISA, WB - ABIN250274 : Carson-Walter, Watkins, Nanda, Vogelstein, Kinzler, St Croix: Cell surface tumor endothelial markers are conserved in mice and humans. in Cancer research 2001 (PubMed)

Weitere Antikörper gegen anthrax Toxin Receptor 1 Interaktionspartner

Human anthrax Toxin Receptor 1 (ANTXR1) Interaktionspartner

  1. These studies identify ANTXR1, a class of receptor that is shared by a mammalian virus and a bacterial toxin, as the cellular receptor for Seneca Valley virus.

  2. Findings suggest that down-regulation of tumor endothelial marker 8 play an important role in the inhibition of tumorigenesis and development of osteosarcoma.

  3. TEM8 may be differentially expressed between wound types and loss of this molecule impacts HaCaT growth and migration, potentially implicating this molecule as a factor involved in successful progression of wound healing.

  4. In the absence of any N-linked glycans, TEM8 fails to fold correctly and is recognized by the ER quality control machinery.

  5. These studies expand the allelic spectrum in this rare condition and potentially provide insight into the role of ANTXR1 in the regulation of the extracellular matrix.

  6. ANTXR2 (zeige ANTXR2 Antikörper) is expressed by human uterine smooth muscle cell and appears important for normal human uterine smooth muscle cell viability, migration and contractility.

  7. High ANTXR1 accelerates breast tumor growth and lung metastasis.

  8. There is an attenuation of ANTXR1 expression post-infection which may be a protective mechanism that has evolved to prevent reinfection.

  9. Mutations affecting ANTXR1 function are responsible for GAPO syndrome's characteristic generalized defect in extracellular-matrix homeostasis.

  10. An acidic region in the cytosolic tail of ANTXR1 decreases actin association, sending a signal that prevents binding of ANTXR1 to the protective antigen and providing evidence that cytoskeletal dynamics regulate ANTXR1 function.

Mouse (Murine) anthrax Toxin Receptor 1 (ANTXR1) Interaktionspartner

  1. Anthrax Toxin Protective Antigen Variants That Selectively Utilize either the CMG2 (zeige ANTXR2 Antikörper) or TEM8 Receptors for Cellular Uptake and Tumor Targeting.

  2. An essential physiologic role for Antxr1 in arteriogenesis and peripheral artery disease.

  3. Data demonstrate that TEM8 is an essential regulator of connective tissue homeostasis. it controls synthesis of major matrix components in both endothelial and fibroblastic cells and regulates signaling pathways and matrix degradation.

  4. These results strongly suggest that TEM8 is the only minor anthrax toxin receptor mediating direct lethality in vivo and that other proteins implicated as receptors do not play this role.

  5. This is the first demonstration that the ATR/TEM8 protein is highly expressed in epithelial cells, suggesting that the ATR/TEM8 expression pattern is highly relevant for understanding the pathogenesis of anthrax infection.

  6. The mRNA transcripts of both receptors, ANTXR1 and ANTXR2 (zeige ANTXR2 Antikörper) were detected in J774A.1 cells and mouse tissues suggesting that anthrax edema toxin and B. anthracis Sterne spore are involved in the ANTXR mRNA regulation in host cells.

  7. Data show that the lethality of anthrax toxin for mice is mostly mediated by CMG2 (zeige ANTXR2 Antikörper) and that TEM8 plays only a minor role.

  8. Host-derived TEM8 promotes the growth of certain tumors.

anthrax Toxin Receptor 1 (ANTXR1) Antigen-Profil

Protein Überblick

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

Genbezeichner und Symbole assoziert mit ANTXR1

  • anthrax toxin receptor 1 (ANTXR1) Antikörper
  • anthrax toxin receptor 1 (Antxr1) Antikörper
  • 2310008J16Rik Antikörper
  • 2810405N18Rik Antikörper
  • Antrx1 Antikörper
  • ANTXR1 Antikörper
  • ATR Antikörper
  • Tem8 Antikörper

Bezeichner auf Proteinebene für ANTXR1

anthrax toxin receptor 1 , tumor endothelial marker 8 , anthrax toxin receptor 1-like , 2310008J16Rik , 2810405N18Rik

GENE ID SPEZIES
470393 Pan troglodytes
612601 Canis lupus familiaris
100061334 Equus caballus
100357637 Oryctolagus cuniculus
100410030 Callithrix jacchus
100425392 Macaca mulatta
100513853 Sus scrofa
100598321 Nomascus leucogenys
84168 Homo sapiens
69538 Mus musculus
362393 Rattus norvegicus
616010 Bos taurus
428199 Gallus gallus
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